Diagnosing feline idiopathic cystitis: Review
DOI:
https://doi.org/10.22256/PUBVET.V11N9.864-876Keywords:
hematuria, cat, polaquiuria, syndrome, lutsAbstract
It is know that the casuistic of cats that present clinical signs referring to the lower urinary tract (STUI) worldwide is enormous. However it is also recognized that, in most of these cases, the specific cause that triggers such signals is not known, as well as signals referring to other systems that may be previously or simultaneously concomitant with STUI. The objective of this work is to investigate the current evidence on feline idiopathic / interstitial cystitis (CIF) and how to approach the feline patient for this syndrome: what questions should be asked to the tutor, the findings of the physical and complementary exams, as well as the treatments most indicated in each particular case.
References
Anjos, T. M. 2014. Urologia em medicina felina. In: Santos, K. K. F. (ed.) Guia prático de nefrologia em cães e gatos. L. F. Livros, Rio de Janeiro, Brasil.
Barry, K. J. & Crowell-Davis, S. L. 1999. Gender differences in the social behavior of the neutered indoor-only domestic cat. Applied Animal Behaviour Science, 64, 193-211.
Bartges, J. 2011. Urethral diseases. In: Bartges, J. & Polzin, D. J. Nephrology and urology of small animals. Wiley-Blackwell, Chichester, West Sussex, ENG.
Birder, L. A., Lobo-Johnston, A., Buffington, C. A., Roppolo, J. R., De Groat, W. C. & Kanai, A. J. 2005. Altered inducible nitric oxide synthase expression and nitric oxide production in the bladder of cats with feline interstitial cystitis. Journal of Urology, 173, 625–629.
Birder, L. A., Nakamura, Y., Kiss. S., Nealen, M. L., Barrick, S., Kanai, A. J., Wang, E., Ruiz, G., De Groat, W. C., Apodaca, Watkins, S. & Caterina, M. J. 2002. Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1. Nature Neuroscience, 5, 856–860.
Borrego, J. F. 2017. Urogenital and mammary gland tumors. In: Ettinger, S.J., Feldman, E.C. & Côte, E. (eds.) Textbook of veterinary internal medicine. Elsevier, St. Louis, Missouri, USA.
Buffington, C. A. T. 2009. Developmental influences on medically unexplained symptoms. Psychotherapy Psychosomatics, 78, 139–144.
Buffington, C. A. T. 2011. Idiopathic vystitis in domestic cats – Beyond the Lower Urinary Tract. Journal of Veterinary Internal Medicine. 25, 784–796.
Buffington, C. A. T. 2017. Feline idiopathic cystitis. In: Ettinger, S. J., Feldman, E. C. & Côte, E. (eds.) Textbook of veterinary internal medicine. Elsevier, St. Louis, Missouri, USA.
Buffington, C. A. T., Blaisdell, J. L., Binns JR, S. P. & Woodworth, B. E. 1996. Decreased urine glycosaminoglycan excretion in cats with interstitial cystitis. Journal of Urology, 155, 1801–1804.
Buffington, C. A. T., Chew, D. J., Kendall, M. S., Scrivani, P. V., Thompson, S. B., Blaisdell, J. L. & Woodworth, B. E. 1997. Clinical evaluation of cats with nonobstructive urinary tract diseases. Journal of the American Veterinary Medical Association, 210, 46–50.
Buffington, C. A. T., Westropp, J. L. & Chew, D. J. 2014. From FUS to Pandora syndrome: Where are we, how did we get here, and where to now?. Journal of Feline Medicine and Surgery, 16, 385-394.
Burnstock, G. Purinergic mechanosensory transduction and visceral pain. 2009. Molecular Pain, 5, 69.
Chew, D. J., Buffington, C. A., Kendall, M. S., Dibartola, S. P. & Woodworth, B. E. 1998. Amitriptyline treatment for severe recurrent idiopathic cystitis in cats. Journal of the American Veterinary Medical Association, 213, 1282–1286.
Chew, D. J., Dibartola, S. P. & Schenck, P. A. 2012a. Uropatia e nefropatia obstrutiva. In:______. (eds.) Urologia e nefrologia do cão de do gato. Saunders Elsevier, Rio de Janeiro, Brasil.
Chew, D. J.,Dibartola, S. P. & Schenck, P. A. 2012b. Cistite intersticial ou idiopática não obstrutiva em gatos. In:______. (eds.) Urologia e nefrologia do cão de do gato. Saunders Elsevier, Rio de Janeiro, Brasil.
Crivellenti, L. Z. 2015. Nefrologia e urologia. In: Crivellenti, L. Z & Crivellenti, S. B. (eds.) Casos de rotina em medicina veterinária de pequenos animais. Medvet, São Paulo, Brasil
Defauw, P. A., Van De Maele, I., Duchateau, G., Polis, I. E., Saunders, J. H. & Daminet, S. 2011. Risk factors and clinical presentation of cats with feline idiopathic cystitis. Journal of Feline Medicine and Surgery, 13, 967–975.
Dibartola, S. P. 2015. Cistite idiopática obstrutiva e não obstrutiva. In: Nelson, R. W. & Couto, C. G. (eds.) Medicina interna de pequenos animais. Mosby Elsevier, Rio de Janeiro, Brasil.
Forrester, S. D. & Roudebush, P. 2007. Evidence-based management of feline lower urinary tract disease. Veterinary Clinics of North America: Small Animal Practice, 37, 533–558.
Gibbin, M. 2010. Interstitial cystitis/painful bladder syndrome. Disponível em: < http://flipper.diff.org/apprulesitems/items/2325>.
Gittleman, J. L. 1989. Carnivore group living: comparative trends. In:______ (ed.). Carnivore behavior, ecology, and evolution. Cornell University Press, Ithaca, NY, USA.
Gunn-Moore, D. A. & Cameron, M. E. A. 2004. Pilot study using synthetic feline facial pheromone for the management of feline idiopathic cystitis. Journal of Feline Medicine and Surgery, 6, 133–138.
Hauser, P. J., Dozmorov, M. G., Bane, B. L., Slobodov, G., Culkin, D. J. & Hurst, R. E. 2008. Abnormal expression of differentiation related proteins and proteoglycan core proteins in the urotheliumof patients with interstitial cystitis. The Journal of Urology, 179, 764–769.
Herron, M. E. 2010. Advances in understanding and treatment of feline inappropriate elimination. Topics in Companion Animal Medicine, 25, 195-202.
Holt, P. E. 2011. Disúria não prostática. In:______. (ed.) Urologia em cães e gatos. Revinter, Rio de Janeiro, Brasil.
Hostutler, R. A., Chew, D. J. & Dibartola, S. P. 2005. Recent concepts in feline lower urinary tract disease. Veterinary Clinics of North America: Small Animal Practice, 35, 147–170.
Hunter, R. G. & McEwen, B. S. 2013. Stress and anxiety across the lifespan: structural plasticity and epigenetic regulation. Epigenomics, 177–194.
Jones, B. R., Sanson, R. L. & Morris, R. S. 1997. Elucidating the risk factors of feline urologic syndrome. New Zeland Veterinary Journal, 45, 100–108.
Kaan, T. K., Yip, P. K., Grist, J., Cefalu, J. S., Nunn, P. A., Ford, A. P., Zhong, Y. & McMahon, S. B. 2010. Endogenous purinergic control of bladder activity via presynaptic P2X3 and P2X2/3 receptors in the spinal cord. Journal of Neuroscience, 30, 4503–4507.
Keay, K. S., Birder, L. A. & Chai, T. C. 2014. Evidence for bladder urothelial pathophysiology in functional bladder disorders. Biomed Research International, 2014, 15.
Labato, M. A. 2017. Lower Urinary Tract Urolithiasis—Feline. In: Ettinger, S.J., Feldman, E.C. & Côte, E. (eds.) Textbook of veterinary internal medicine. Elsevier, St. Louis, Missouri, USA.
Lavelle, J. P., Meyers, S. A., Ruiz, W. G., Buffington, C. A., Zeidel, M. L. & Apodaca, L. 2000. Urothelial pathophysiological changes in feline interstitial cystitis: a human model. American Journal of Physiology - Renal Physiology, 278, F540–553.
Lee, J. A. & Drobatz, K. J. 2003. Characterization of the clinical characteristics, electrolytes, acid-base, and renal parameters in male cats with urethral obstruction. Journal Veterinary Emergency and Critical Care, 13, 227–233.
Liu, H. T. & Kuo H. C. Intravesical botulinum toxin A injections plus hydrodistension can reduce nerve growth fator production and control bladder pain in interstitial cystitis. 2007. Urology, 70, 463–468.
Mayer-Roenne, B., Goldstein, R. E. & Erb, H. N. Urinary tract infections in cats with hyperthyroidism, diabetes mellitus and chronic kidney disease. 2007. Journal of Feline Medicine Surgery, 9, 124–132.
Micera, A., Lambiase, A. Stampachiacchiere, B., Bonini, S., Bonini, S. & Levi-Schaffer, F. 2007. Nerve growth factor and tissue repair remodeling: trkANGFR and p75NTR, two receptors one fate. Cytokine & Growth Factor Reviews, 18, 245–256.
Nunes, M. B. S. F. 2015. Cistite idiopática felina. Dissertação (Mestrado) – Universidade de Évora, Escola de Ciência e Tecnologia.
Osborne, C. A., Lulich, J. P., Polzin, D. J. 2011. Feline urethral obstruction. In: Bartges, J., Polzin, D. J. (eds.) Nephrology and urology of small animals. Wiley-Blackwell, Chichester, West Sussex, ENG.
Pageat, P. & Gaultier, E. Current research in canine and feline pheromones. 2003. Veterinary Clinics of North America: Small Animal Practice, 33, 187–211.
Park, R. D. & Wrigley, R. H. 2010. Bexiga urinária. In: Thrall, D. E. (ed.) Diagnóstico de radiologia veterinária. Saunders Elsevier, Rio de Janeiro, Brasil.
Pereira, D. A., Aguiar, J. A., Hagiwara, M, K. & Michelacci, Y. M. 2004. Changes in cat urinary glycosaminoglycans with age and in feline urologic syndrome. Biochimica et Biophysica Acta, 1672, 1–11.
Persu, C., Cauni, V., Gutue, S., Blaj, I., Jinga, V. & Geavlete, P. From interstitial cystitis to chronic pelvic pain. 2010. Journal of Medicine and Life, 3, 167-174.
Press, S. M., Moldwin, R., Kushner, L. et al. 1995. Decreased expression of GP-51 glycosaminoglycan in cats afflicted with feline interstitial cystitis. Journal of Urology, 153, 288A.
Reche, A. & Camozzi, R. B. 2015. Doença do trato urinário inferior dos felinos | cistite intersticial. In: Jericó, M. M., Neto, J. P. A. & Kogika, M. M. (eds.) Tratado de medicina interna de cães e gatos. Roca, Rio de Janeiro, Brasil.
Rodrigues, P. Síndrome da Bexiga Dolorosa Ou Cistite Intersticial. Disponível em <http://www.drpaulorodrigues.com.br/patologia/sindrome-da-bexiga-dolorosa-cistite-intersticial/>.
Sands, S. A., Strong, R., Corbitt, J. & Morilak, D. A. 2000. Effects of acute restraint stress on tyrosine hydroxylase mRNA expression in locus coeruleus of Wister and Wistar-Kyoto rats. Molecular Brain Research, 75, 1–7.
Slobodov, G., Feloney, M., Gran, C., Kyker, K. D., Hurst, R. E. & Culkin, D. J. 2004. Abnormal expression of molecular markers for bladder impermeability and differentiation in the urothelium of patients with interstitial cystitis. Journal of Urology, 171, 1554–1558.
Stella, J. L., Lord L. K. & Buffington, C. A. Sickness behaviors in response to unusual external events in healthy cats and cats with feline interstitial cystitis. 2011. Journal of the American Veterinary Medical Association. 238, 67–73.
Stevens, C. W. & Brenner, G. M. 1996. Spinal administration of adrenergic agents produces analgesia in amphibians. European Journal of Pharmacology, 316, 205–210.
Tabar Rodríguez, M. D., Planellas Bachs, M. 2012. Doença do trato urinário inferior felino. In: Cortadellas, O. (ed.) Manual de nefrologia e urologia clínica canina e felina. Medvet, São Paulo, Brasil.
Veranic, P. & Jezernik, K. The response of junctional complexes to induced desquamation in mouse bladder urothelium. 2000. Biology of the Cell, 92, 105–113.
Westropp, J. L. 2011. Feline idiopathic cystitis. In: Bartges, J., Polzin, D. J. (eds.) Nephrology and urology of small animals. Wiley-Blackwell, Chichester, West Sussex, ENG.
Westropp, J. L., Kass, P. H. & Buffington, C. A. T. In vivo evaluation of the alpha-2 adrenoceptors in cats with idiopathic cystitis. 2007. American Journal of Veterinary Research, 68, 203–207.
Westropp, J. L., Welk, K. A. & Buffington, C. A. T. 2003. Small adrenal glands in cats with feline interstitial cystitis. Journal of Urology, 170, 2494–2497.
Willeberg, P. 1984. Epidemiology of naturally occurring feline urologic syndrome. Veterinary Clinics of North America Small Animal Practice, 14, 455– 469.
Downloads
Published
Issue
Section
License
Copyright (c) 2017 Murilo Ramos Bastos de Oliveira, Catarina Rafaela Alves da Silva, Kennya Cristina Damasceno de Jesus, Karoline Figueredo Rodrigues, Raquel Albuquerque Silva, Sergio Diego Passos Costa, Francisco Lima Silva, Marcelo Campos Rodrigues
This work is licensed under a Creative Commons Attribution 4.0 International License.
Você tem o direito de:
Compartilhar — copiar e redistribuir o material em qualquer suporte ou formato
Adaptar — remixar, transformar, e criar a partir do material para qualquer fim, mesmo que comercial.
O licenciante não pode revogar estes direitos desde que você respeite os termos da licença. De acordo com os termos seguintes:
Atribuição
— Você deve dar o crédito apropriado, prover um link para a licença e indicar se mudanças foram feitas. Você deve fazê-lo em qualquer circunstância razoável, mas de nenhuma maneira que sugira que o licenciante apoia você ou o seu uso. Sem restrições adicionais
— Você não pode aplicar termos jurídicos ou medidas de caráter tecnológico que restrinjam legalmente outros de fazerem algo que a licença permita.
