Evaluation of pharmacological treatments for dermatophytoses in pet animals

Abstract

Dermatophytoses are skin infections that can be transmitted from the infected to companion animals or to humans. It is caused by keratinophilic fungi called dermatophytes. The objective of this work is to evaluate the pharmacological treatments for dermatophytoses in companion animals of the animals treated at the University Veterinary Clinic of the Pontifical Catholic University of Paraná - PUCPR Campus Toledo in the period from March 15, 2017 to August 08, 2017 and compare them to the bibliography. The agents most frequently found in this type of infection are of the genus Microsporum sp., Trichophyton sp. and Epidermophyton sp. They cause alopecia lesions, erythema, crusting and pruritus, requiring laboratory identification to confirm the diagnosis and may have long treatment or even reinfections, depending on therapeutic combinations for complete cure. It was evaluated nine cases, one case of feline species and eight cases of canine species. The most frequent lesion in cases of dermatophytosis was alopecia, allergy, pruritus and erythema. The most frequent fungal isolates in this study were Trichophyton sp. identified in eight animals of the canine species, and for the feline species Penicillium sp. a case. For the treatments used, they were mostly through shampoos containing antimicrobial and antiseptic drugs in their formulation, followed by systemic use of oclacitinib maleate, fluconazole, itraconazole, respectively. It was also observed the association of the baths with shampoo and medications of systemic use corroborating with the consulted bibliography, since the association of the topical and systemic therapies reduces the time of infection of the animal. Topical use through ointments was observed in two cases, one being in the feline where it replaced the bath with the shampoo.