Pre-axial longitudinal hemimelia associated with humeral hypoplasia in dog: Case repor

Abstract

Changes in embryogenesis may produce abnormalities in the structure or function of tissues and organs and these may be of genetic or environmental origin. The process known as organogenesis will depend on the interaction between endoderm, mesoderm and ectoderm, which will originate subsequent cellular movements, through the migration of precursor cells with the formation of the limb buds and thus causing cytodifferentiation, that is, in the formation of the limbs themselves. The disostoses, which are the set of congenital morphological alterations, are characterized by the abnormal development of a bone or part of it, which can affect the appendicular skeleton. Agenesis, or also known as hemimelia, consists of a rare character anomaly in which one or more paired bones have complete or partial absence, but among this rarity the most frequent is hemimelia in the unilateral form. The case report is a dog, SRD, presenting a left thoracic limb deformity, limping and unable to support it to the ground. Radiographic examinations of the limb were performed consecutively, which revealed the presence of pre-axial longitudinal hemimelia associated with humeral hypoplasia. It was decided to wait for the development of the animal for clinical reassessment and development of prosthesis in the affected limb.