Thoracoabdominal reconstruction with polypropylene mesh after excision of chondroblastic osteosarcoma in a dog
DOI:
https://doi.org/10.31533/pubvet.v18n11e1680Keywords:
arco costal, cão, cirurgia oncológica, osteossarcoma, tela de polipropilenoAbstract
Osteosarcoma is the main bone neoplasm originating in the costal arches; however, its occurrence is less common than that of appendicular osteosarcoma. Known to be locally invasive and with high metastatic potential, it generally requires multimodal treatment involving aggressive surgery and adjuvant chemotherapy. This study aims to report an unusual case of costal arch osteosarcoma in a one-year-old Pit bull dog, who underwent resection of five ribs aiming at wide tumor resection, with subsequent reconstruction of the thoracoabdominal wall using polypropylene mesh. After surgical resection of the tumor, adjuvant antineoplastic chemotherapy with doxorubicin and carboplatin was performed at 21-day intervals, totaling six cycles. To date, the patient has shown no signs of local recurrence or metastases, with a disease-free period of 16 months.
References
Athanassiadi, K., Theakos, N., Kalantzi, N., & Gerazounis, M. (2010). Prognostic factors in flail-chest patients. European Journal of Cardio-Thoracic Surgery, 38(4), 466-471. Doi: https://doi.org/10.1016/j.ejcts.2010.02.034
Bacon, N. J., Ehrhart, N. P., Dernell, W. S., Lafferty, M., & Withrow, S. J. (2008). Use of alternating administration of carboplatin and doxorubicin in dogs with microscopic metastases after amputation for appendicular osteosarcoma: 50 cases (1999–2006). Journal of the American Veterinary Medical Association, 232(10), 1504-1510. Doi: https://doi.org/10.2460/javma.232.10.1504
Bailey, D., Erb, H., Williams, L., Ruslander, D., & Hauck, M. (2003). Carboplatin and doxorubicin combination chemotherapy for the treatment of appendicular osteosarcoma in the dog. Journal of veterinary internal medicine, 17(2), 199-205. Doi: https://doi.org/10.1111/j.1939-1676.2003.tb02434.x
Baines, S. J., Lewis, S., & White, R. A. S. (2002). Primary thoracic wall tumours of mesenchymal origin in dogs: A retrospective study of 46 cases. Veterinary Record, 150(11), 335-339. Doi: 10.1136/vr.150.11.335
Benlloch-Gonzalez, M., & Poncet, C. (2015). Sternal cleft associated with Cantrell’s pentalogy in a German Shepherd dog. Journal of the American Animal Hospital Association, 51, 279–284. Doi: https://doi.org/10.5326/JAAHA-MS-6181
Boerman, I., Selvarajah, G. T., Nielen, M., & Kirpensteijn, J. (2012). Prognostic factors in canine appendicular osteosarcoma–A meta-analysis. BMC Veterinary Research, 8, 1-12. Doi: 10.1186/1746-6148-8-56
Brodey, R. S., & Riser, W. H. (1969). 7 Canine Osteosarcoma: A Clinicopathologic Study of 194 Cases. Clinical Orthopaedics and Related Research (1976-2007), 62, 54-64.
Brodey, R. S. (1979). The use of naturally occurring cancer in domestic animals for research into human cancer: general considerations and a review of canine skeletal osteosarcoma. The Yale journal of biology and medicine, 52(4), 345.
Cavalcanti, J. N., Amstalden, E. M. I., Guerra, J. L., & Magna, L. C. (2004). Osteosarcoma in dogs: clinical-morphological study and prognostic correlation. Brazilian Journal of Veterinary Research and Animal Science, 41, 299-305. Doi: https://doi.org/10.1590/S1413-95962004000500002
Chun, R., Kurzman, I. D., Couto, C. G., Klausner, J., Henry, C., & MacEwen, E. G. (2000). Cisplatin and doxorubicin combination chemotherapy for the treatment of canine osteosarcoma: a pilot study. Journal of Veterinary Internal Medicine, 14(5), 495-498. Doi: https://doi.org/10.1111/j.1939-1676.2000.tb02265.x
Cole, S., Gianferante, D. M., Zhu, B., & Mirabello, L. (2022). Osteosarcoma: a surveillance, epidemiology, and end results program‐based analysis from 1975 to 2017. Cancer, 128(11), 2107-2118. Doi: https://doi.org/10.1002/cncr.34163
Cooley, D. M., & Waters, D. J. (1997). Skeletal neoplasms of small dogs: a retrospective study and literature review. Journal of the American Animal Hospital Association, 33(1), 11-23. Doi: https://doi.org/10.5326/15473317-33-1-11
Costa, F. S., Tostes, R. A., Farias, M. R. D., Sampaio, R. L., & Perez, J. A. (2001). Metástase cutânea de osteossarcoma em um cão: relato de caso. Brazilian Journal of Veterinary Research and Animal Science, 38, 240-242. Doi: https://doi.org/10.1590/S1413-95962001000500008
Cordella, A., De Santis, F., Franchini, I., & Rossi, F. (2023). CT features of primary bone neoplasia of the thoracic wall in dogs. Veterinary Radiology & Ultrasound, 64(4), 605-614. Doi: https://doi.org/10.1111/vru.13236
Davis, S. D. (1991). CT evaluation for pulmonary metastases in patients with extrathoracic malignancy. Radiology, 180(1), 1-12.
Dernell W.S., Straw R.C. & Withrow S.J. (2001). Tumors of the skeletal system, p.378-417. In: MacEwen E. (Ed), Small Animal Clinical Oncology, 3rd ed. W.B. Saunders, Philadelphia.
Dernell W.S., Erhardt N.P., Straw R.C. and Vail D.M. (2007). Withrow and McEwen’s small animal clinical oncology. In: Saunders Elsevier, 4th edn., SJ Withrow and DM Vail eds., St Louis, MO, 540–582.
Dickerson, M. E., Page, R. L., LaDue, T. A., Hauck, M. L., Thrall, D. E., & Steyn, P. F. (2001). Retrospective analysis of axial skeleton osteosarcoma in 22 large-breed dogs. Journal of Veterinary Internal Medicine, 15(2), 120-124. Doi: https://doi.org/10.1111/j.1939-1676.2001.tb01242.x
Eberle, N., Mischke, R., Nolte, I., & Betz, D. (2011). Comparison of examination of thoracic radiographs and thoracic computed tomography in dogs with appendicular osteosarcoma. Veterinary and Comparative Oncology, 9(2), 131-140. Doi: https://doi.org/10.1111/j.1476-5829.2010.00241.x
Edmunds, G. L., Smalley, M. J., Beck, S., Errington, R. J., Gould, S., Winter, H., ... & O’Neill, D. G. (2021). Dog breeds and body conformations with predisposition to osteosarcoma in the UK: a case-control study. Canine medicine and genetics, 8, 1-22.
Egenvall, A., Nødtvedt, A., & von Euler, H. (2007). Bone tumors in a population of 400 000 insured Swedish dogs up to 10 y of age: incidence and survival. Canadian Journal of Veterinary Research, 71(4), 292.
Feeney, D. A., Johnston, G. R., Grindem, C. B., Toombs, J. P., Caywood, D.D., & Hanlon, G. F. (1982). Malignant neoplasia of canine ribs: Clinical, radiographic, and pathologic findings. Journal of the American Veterinary Medical Association, 180, 927–933.
Frimberger, A. E., Chan, C. M., & Moore, A. S. (2016). Canine osteosarcoma treated by post-amputation sequential accelerated doxorubicin and carboplatin chemotherapy: 38 cases. Journal of the American Animal Hospital Association, 52(3), 149-156. Doi: https://doi.org/10.5326/JAAHA-MS-6315
Gianferante, D. M., Mirabello, L., & Savage, S. A. (2017). Germline and somatic genetics of osteosarcoma—connecting aetiology, biology and therapy. Nature Reviews Endocrinology, 13(8), 480-491.
Gomes, L.C., Brandão, C.V.S., Ranzani, J.J.T. (2008). Osteossarcoma canino: revisão. Vet e Zootec. 15: 204-219.
Gorman, E., Barger, A. M., Wypij, J. M., & Pinkerton, M. E. (2006). Cutaneous metastasis of primary appendicular osteosarcoma in a dog. Veterinary clinical pathology, 35(3), 358-361. Doi: https://doi.org/10.1111/j.1939-165X.2006.tb00149.x
Hammer, A. S., Weeren, F. R., Weisbrode, S. E., & Padgett, S. L. (1995). Prognostic factors in dogs with osteosarcomas of the flat or irregular bones. Journal of the American Animal Hospital Association, 31(4), 321-326.
Heyman, S. J., Diefenderfer, D. L., Goldschmidt, M. H., & Newton, C. D. (1992). Canine axial skeletal osteosarcoma a retrospective study of 116 cases (1986 to 1989). Veterinary Surgery, 21(4), 304-310.
Hillers, K. R., Dernell, W. S., Lafferty, M. H., Withrow, S. J., & Lana, S. E. (2005). Incidence and prognostic importance of lymph node metastases in dogs with appendicular osteosarcoma: 228 cases (1986–2003). Journal of the American Veterinary Medical Association, 226(8), 1364-1367. Doi: https://doi.org/10.2460/javma.2005.226.1364
Hirakata, K., Nakata, H., & Nakagawa, T. (1995, October). CT of pulmonary metastases with pathological correlation. In Seminars in Ultrasound, CT and MRI (Vol. 16, No. 5, pp. 379-394). WB Saunders. Doi: https://doi.org/10.1016/0887-2171(95)90027-6
Idoate, M. Á., Aquerreta, J. D., Lamo-Espinosa, J. M., & San-Julian, M. (2022). A reassessment of the barrier effect of the physis against metaphyseal osteosarcoma: a comprehensive pathological study with its radiological and clinical follow-up correlations. Diagnostics, 12(2), 450. Doi: https://doi.org/10.3390/diagnostics12020450
Jongeward, S. J. (1985). Primary bone tumors. Veterinary clinics of North America: small animal practice, 15(3), 609-641. Doi: https://doi.org/10.1016/S0195-5616(85)50061-3
Kent, M. S., Strom, A., London, C. A., & Seguin, B. (2004). Alternating carboplatin and doxorubicin as adjunctive chemotherapy to amputation or limb‐sparing surgery in the treatment of appendicular osteosarcoma in dogs. Journal of Veterinary Internal Medicine, 18(4), 540-544. Doi: https://doi.org/10.1111/j.1939-1676.2004.tb02582.x
Kirpensteijn, J., Kik, M., Rutteman, G. R., & Teske, E. (2002). Prognostic significance of a new histologic grading system for canine osteosarcoma. Veterinary pathology, 39(2), 240-246. Doi: https://doi.org/10.1354/vp.39-2-240
Kleiner J.A. & Silva E.G. (2003). Tumores ósseos em pequenos animais. Medvep. 1(3): 193-200.
Liptak, J. M., Dernell, W. S., Withrow, S. J., & Lana, S. E. (2008). Reconstruction of chest wall defects after rib tumor resection: A comparison of autogenous, prosthetic, and composite techniques in 44 dogs. Veterinary Surgery, 37(5), 479-487. Doi: https://doi.org/10.1111/j.1532-950X.2008.00413.x
Losken, A., Thourani, V. H., Carlson, G. W., Jones, G. E., Culbertson, J. H., Miller, J. I., & Mansour, K. A. (2004). A reconstructive algorithm for plastic surgery following extensive chest wall resection. British Journal of Plastic Surgery, 57(4), 295-302. Doi: https://doi.org/10.1016/j.bjps.2004.02.004
Loukopoulos, P., & Robinson, W. F. (2007). Clinicopathological relevance of tumour grading in canine osteosarcoma. Journal of comparative Pathology, 136(1), 65-73. Doi: https://doi.org/10.1016/j.jcpa.2006.11.005
Mansour, K. A., Thourani, V. H., Losken, A., Reeves, J. G., Miller, J. I., Carlson, G. W., & Jones, G. E. (2002). Chest wall resections and reconstruction: A 25-year experience. The Annals of Thoracic Surgery, 73(6), 1720-1726. Doi: https://doi.org/10.1016/S0003-4975(02)03527-0
Matthiesen, D. T., Clark, G. N., Orsher, R. J., Pardo, A. O., Glennon, J., &Patnaik, A. K. (1992). En bloc resection of primary rib tumors in 40 dogs. Veterinary Surgery, 21, 201–204. https://doi.org/10.1111/j.1532-950x.1992.tb00046.x
McNeill, C. J., Overley, B., Shofer, F. S., Kent, M. S., Clifford, C. A., Samluk, M., & Sorenmo, K. U. (2007). Characterization of the biological behaviour of appendicular osteosarcoma in Rottweilers and a comparison with other breeds: a review of 258 dogs. Veterinary and Comparative Oncology, 5(2), 90-98. Doi: https://doi.org/10.1111/j.1476-5829.2006.00116.x
Moore, A. S., Dernell, W. S., Ogilvie, G. K., Kristal, O., Elmslie, R., Kitchell, B., ... & Warren, D. (2007). Doxorubicin and BAY 12–9566 for the treatment of osteosarcoma in dogs: a randomized, double‐blind, placebo‐controlled study. Journal of veterinary internal medicine, 21(4), 783-790. Doi: https://doi.org/10.1111/j.1939-1676.2007.tb03022.x
Morello, E., Martano, M., & Buracco, P. (2011). Biology, diagnosis and treatment of canine appendicular osteosarcoma: Similarities and differences with human osteosarcoma. The Veterinary Journal, 189(3), 268-277. Doi: https://doi.org/10.1016/j.tvjl.2010.08.014
Mueller, F., Fuchs, B., & Kaser-Hotz, B. (2007). Comparative biology of human and canine osteosarcoma. Anticancer research, 27(1A), 155-164.
Neuwald, E.B., Veiga, D.C., Gomes, C, Oliveira, E.C., Contesini, E.A. (2006). Osteossarcoma craniano em um cão. Acta Scientiae Veterinariae. 34: 215-219.
Oliveira, F., & Silveira, P. R. (2008). Osteossarcoma em cães (revisão de literatura). Revista científica eletrônica de Medicina Veterinária, 4(11), 1-7.
Peremans, K., Otte, A., Verschooten, F., Van Bree, H., & Dierckx, R. (2003). Soft tissue metastasis of an osteosarcoma of the humerus in a four-legged patient. European Journal of Nuclear Medicine & Molecular Imaging, 30(1). Doi: 10.1007/s00259-002-1041-9
Pirkey-Ehrhart, N., Withrow, S. J., Straw, R. C., Ehrhart, E. J., Page, R. L.,Hottinger, H. L., Hahn, K. A., Morrison, W. B., Albrecht, M. R., & Hedlund, C. S. (1995). Primary rib tumors in 54 dogs. Journal of the American Animal Hospital Association, 31, 65–69. Doi: https://doi.org/10.5326/15473317-31-1-65
Poon, A. C., Matsuyama, A., & Mutsaers, A. J. (2020). Recent and current clinical trials in canine appendicular osteosarcoma. The Canadian Veterinary Journal, 61(3), 301.
Retirar, S.J., Vail, D.M., Page, R.L (2013). Oncologia clínica de pequenos animais de Withrow & MacEwen.5ª edição. Louis, Missouri: Elsevier/Saunders; pág. 143–8
Rodrigues, B. A., Faraco, C., Oliveira, R., Cheuiche, S., Teixeira, F. S., Kirst, C., ... & Sousa, E. M. (2009). Pelvic osteosarcoma ressection in a bitch: case report. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 61, 35-41. Doi: https://doi.org/10.1590/S0102-09352009000100006
Ru, G., Terracini, B., & Glickman, L. T. (1998). Host related risk factors for canine osteosarcoma. The Veterinary Journal, 156(1), 31-39.
Sabattini, S., Stefanello, D., Dentini, A., Bo, S., & Bettini, G. (2017). Comparative assessment of the accuracy of cytological and histologic biopsies in the diagnosis of canine bone lesions. Journal of Veterinary Internal Medicine, 31(3), 864-871. Doi: https://doi.org/10.1111/jvim.14696
Sapierzyński, R., & Czopowicz, M. (2017). The animal-dependent risk factors in canine osteosarcomas. Polish Journal of Veterinary Sciences. Doi: 10.1515/pjvs-2017-0035
Schmidt, A. F., Nielen, M., Klungel, O. H., Hoes, A. W., De Boer, A., Groenwold, R. H. H., ... & VSSO Investigators. (2013). Prognostic factors of early metastasis and mortality in dogs with appendicular osteosarcoma after receiving surgery: an individual patient data meta-analysis. Preventive veterinary medicine, 112(3-4), 414-422. Doi: https://doi.org/10.1016/j.prevetmed.2013.08.011
Schott, C. R., VanWinkle, T. J., & Duda, L. (2018). Histologic grade does not predict outcome in dogs with appendicular osteosarcoma receiving the standard of care. Veterinary Pathology, 55(2), 202-211. Doi: https://doi.org/10.1177/03009858177473
Selmic, L. E., Burton, J. H., Thamm, D. H., Withrow, S. J., & Lana, S. E. (2014). Comparison of carboplatin and doxorubicin‐based chemotherapy protocols in 470 dogs after amputation for treatment of appendicular osteosarcoma. Journal of Veterinary Internal Medicine, 28(2), 554-563. Doi: https://doi.org/10.1111/jvim.12313
Selvarajah, G. T., & Kirpensteijn, J. (2010). Prognostic and predictive biomarkers of canine osteosarcoma. The veterinary journal, 185(1), 28-35. Doi: https://doi.org/10.1016/j.tvjl.2010.04.010
Silva, F. M. F., Moura, V. M. B. D., Pontes, C. R., & Carvalho, Y. K. (2015). Osteossarcoma condroblástico atípico no esqueleto axial em cão. Semina: Ciências Agrárias, 36(4), 295-300. Doi: https://doi.org/10.5433/1679-0359.2015v36n1p295
Silver, K. I., Lurie, D. M., Liptak, J. M., LaDue, T., & Selmic, L. E. (2023). Patterns of metastatic progression and association with clinical outcomes in canine osteosarcoma: A necropsy study of 83 dogs. Veterinary and Comparative Oncology, 21(4), 646-655. Doi: https://doi.org/10.1111/vco.12927
Simpson, S., Dunning, M. D., de Brot, S., Grau-Roma, L., Mongan, N. P., & Rutland, C. S. (2017). Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics. Acta Veterinaria Scandinavica, 59, 1-11.
Simpson, S., Dunning, M., de Brot, S., Alibhai, A., Bailey, C., Woodcock, C. L., ... & Rutland, C. S. (2020). Molecular characterisation of canine osteosarcoma in high risk breeds. Cancers, 12(9), 2405. Doi: https://doi.org/10.3390/cancers12092405
Skorupski, K. A., Rodriguez, C. O., Krick, E. L., Clifford, C. A., Ward, R. L., & Kent, M. S. (2016). Carboplatin versus alternating carboplatin and doxorubicin for the adjuvant treatment of canine appendicular osteosarcoma: A randomized, phase III trial. Veterinary and Comparative Oncology, 14(1), 81-87. Doi: https://doi.org/10.1111/vco.12069
Spodnick, G. J., Berg, J., Rand, W. M., Schelling, S. H., Couto, G., Harvey, H. J., ... & Withrow, S. J. (1992). Prognosis for dogs with appendicular osteosarcoma treated by amputation alone: 162 cases (1978-1988). Journal of the American Veterinary Medical Association, 200(7), 995-999.
Tamura, K., Sasaki, A., Yoshida, K., & Kinoshita, T. (2024). Reconstruction surgery using polypropylene mesh after extensive resection of a costal osteosarcoma in a dog. Veterinary Medicine and Science, 10(2), e31389. Doi: https://doi.org/10.1002/vms3.1389
Teixeira, L. V., Bonagura, J. D., & Lopes, F. (2010). Estudo clínico de osteossarcoma canino. Acta Scientiae Veterinariae, 38(2), 185-190.
Thompson, K. (2007). Bones and Joints, p.1-184. In: Maxxie M.G. (Ed.), Jubb, Kennedy and Palmer’s Pathology of Domestic Animals. 5th ed. Mosby El-sevier, St Louis.
Thompson, K. G., & Pool, R. R. (2002). Tumors of bones. Tumors in domestic animals, 4, 245-317.
Tobias KM, Johnston SA. Cirurgia veterinária: pequenos animais. São Luís: ElseÿVier Saunders; 2012.
Trost, M. E., Souza, F. H. A., Nogueira, C. E. W., & Flores, M. M. (2012). Primary bone neoplasms in dogs: 90 cases. Pesquisa Veterinária Brasileira, 32(12), 1329-1335. Doi: https://doi.org/10.1590/S0100-736X2012001200018
Tuohy, J. L., Worley, D. R., & Bianco, D. (2019). Demographic characteristics, site and phylogenetic distribution of dogs with appendicular osteosarcoma: 744 dogs (2000-2015). PloS One, 14(12), e0223243. Doi: https://doi.org/10.1371/journal.pone.0223243
Warner, G. C., & Cox, G. J. (2003). Evaluation of chest radiography versus chest computed tomography in screening for pulmonary malignancy in advanced head and neck cancer. Journal of otolaryngology, 32(2).
Weyant, M. J., Bains, M. S., Venkatraman, E., Downey, R. J., Park, B., Flores, R. M., & Rusch, V. W. (2006). Results of chest wall resection and reconstruction with and without rigid prosthesis. The Annals of Thoracic Surgery, 81(1), 279-285. Doi: https://doi.org/10.1016/j.athoracsur.2005.07.001
Withrow, S. J., Page, R., & Vail, D. M. (2012). Withrow and MacEwen's small animal clinical oncology. Elsevier Health Sciences.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Jéssica Martinelli Victorino, Petra Cavalcanti Germano, Sabrina Marin Rodigheri, Vinicius Gonzalez Peres Albernaz
This work is licensed under a Creative Commons Attribution 4.0 International License.
Você tem o direito de:
Compartilhar — copiar e redistribuir o material em qualquer suporte ou formato
Adaptar — remixar, transformar, e criar a partir do material para qualquer fim, mesmo que comercial.
O licenciante não pode revogar estes direitos desde que você respeite os termos da licença. De acordo com os termos seguintes:
Atribuição
— Você deve dar o crédito apropriado, prover um link para a licença e indicar se mudanças foram feitas. Você deve fazê-lo em qualquer circunstância razoável, mas de nenhuma maneira que sugira que o licenciante apoia você ou o seu uso. Sem restrições adicionais
— Você não pode aplicar termos jurídicos ou medidas de caráter tecnológico que restrinjam legalmente outros de fazerem algo que a licença permita.
