The function of sertoli cells in spermatogenesis

Abstract

The Sertoli cell is an example of cell with specializations structural that carry out several functions simultaneously. They associate at the same time with at least four different types of germinatives cells, propitiating like this conditions for the progression and differentiation of these during the spermatogenesis, with the basal membrane and with other Sertoli cells. The Sertoli cells exercise vital function in the regulation of the spermatogenesis, therefore any dysfunction of these it can cause alterations and or degenerations of the germinatives cells and infertility. The Sertoli cells have several functions as: it controls of the maturation and of the migration of the germinatives cells; synthesis of proteins and steroids, are involved in the control of the passage of the secretions among tubular and interstitial compartments and, they form the hemato testicular barrier. The spermatic production daily for gram of testicle is used as parameter for evaluation of the efficiency of the spermatogenesis and it can be related with: the number of Sertoli cells for gram of testicle, the capacity of support of the Sertoli cell, the volumetric density of the seminific tubules in the testicle (%), the number of spermatogonias generations and to smallest loss of germinatives cells during the spermatogenesis. The objective of this revision is to explain the function of the Sertoli cells in spermatogenesis, since it is made such necessary understanding for evaluations and interpretations of some cases of infertility.