Clinical evaluation of detomidine hydrochloride in sheep

Abstract

The purpose of this study was to describe the clinical effects of the use of detomidine hydrochloride in the ovine species. Eight sheep that were healthy, female gender and adults in the dry lactation period were used for this research. Detomidine hydrochloride was administered in the dose of 30 µg/kg IM. The following parameters: heart and respiratory rates, T°C, ruminal movements, and evaluations of the degree of sedation, posture and lowering of the head; were measured before the administration of this drug, and after every 15 minutes until 120 minutes of observation were completed. Sternal decubitus was observed at 15 minutes after the administration of detomidine hydrochloride in all animals in this study. In the first 15 minutes, a decrease in heart and respiratory rates, and ruminal motility was noticed. After this period, a gradual increase in heart rate was detected, however persisting 33% lower of basal values at 120 minutes of observation. The respiratory rate and ruminal motility returned to the basal values at the end of experimental period. The rectal temperature decreased in the first 75 minutes, returning to the basal values at the end of the study. In terms of this experimental study, the results indicates that detomidine hydrochloride promotes sedative effect in ovine, without causing significant adverse effects, recommended has a preanesthesic drug and tranquilizer in this species.