Renal laboratory abnormalities in dogs with visceral leishmaniasis naturally infected

Abstract

The Canine Visceral Leishmaniasis (CVL) is a zoonosis of great relevance in Brazil resulting in most of the times a kidney disease that can be the only manifestation in dogs with CVL and can progress to the stage of renal failure. 12 dogs were used, mongrel dogs, males divided into 2 groups. The first formed by negative dogs with serology and parasitology for CVL and the second positive. Animal blood samples were collected for biochemical analysis selected from urea, creatinine, total protein and globulin, and urine samples for urinalysis of. Hyperproteinaemia to hyperglobulinemia, as well as increased presence of albumin in urine were found in the relevant positive dogs. It was observed in the mean values of urea and creatinine, as well as, the protein concentration in urine of positive animals. The biochemical changes observed showed agreement with the results found in the literature, demonstrating that in patients positive for CVL renal dysfunction is of great importance to aid in the clinical staging.