Gastric mucinous adenocarcinoma associated with helicobacteriosis and paracoccidioidomycosis in a bitch
DOI:
https://doi.org/10.31533/pubvet.v19n03e1744Keywords:
bacteria, neoplasm, infection, ringworm, stomachAbstract
Gastric tumors in dogs are an uncommon pathology within neoplasms, and can present themselves by several factors such as the presence of antigens, in this context, this material addresses morphological and histopathological aspects of a case of gastric mucinous adenocarcinoma associated with helicobacteriosis and paracoccidioidomycosis in a 12-year-old chow-chow dog who had recurrent emesis with decreased appetite, and that she underwent partial gastrectomy. Ultrasound examination showed hyperechoic lesions in the gastric mucosa and sharply thickened walls, so endoscopy was requested, which demonstrated the existence of multiple ulcerative lesions and mucosa containing metaplasias, necrotic points and hemorrhagic foci. Next, a biopsy of the gastric mucosa was performed, in which 16 fragments were sent for histopathological analysis, and neoplastic proliferation of epithelial origin with malignant biological behavior was found. It was also possible through this analysis to diagnose the patient with mucinous adenocarcinoma, which is classified as invasive due to its disposition and tissue organization in the stomach; Chronic inflammatory reactions were also found associated with structures compatible with helicobacteriosis and paracoccidioidomycosis, possibly also related to dysplasia. This case report aims to correlate the tumor diagnosis with fungal and bacterial infection, seeking to associate the emergence and progression of the pathology with the aforementioned antigens (Helicobacter spp. and Paracoccidioides spp.), based on other literature that discusses similar cases and/or the profile of the antigens described.
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