Canine leptospirosis: A clinical approach and the importance of epidemiological diagnosis in the city of Seropédica, Rio de Janeiro, Brazil

Authors

DOI:

https://doi.org/10.31533/pubvet.v17n9e1446

Keywords:

Medical clinic, infection, renal failure, public health, zoonosis

Abstract

In the present work, our objective was to evaluate canine leptospirosis in the context of public health, given that dogs act as sentinels of the disease. For this, an epidemiological survey of 10 suspected animals was carried out, which were treated in the region of Seropédica, Rio de Janeiro. Each animal’s history, where it lived, if it had contact with rodents and the possibility of contact with contaminated water were the initial parameters to arrive at suspicion of the disease. Along with this, parameters observed in the clinical examination plus laboratory alterations in the blood count and in some biochemical markers were used as criteria to reach the diagnosis, since serology would be needed for confirmation. Considering that canine leptospirosis is a highly lethal zoonosis, and the existence of subclinical cases, the epidemiological study is of great importance in this context, as one of the tools for clinical diagnosis of the disease in the absence of a confirmatory serological test.

References

Barone, G. (2015). Tratado de medicina veterinária. Guanabara Koogan S.A.

Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. (2009). Guia Leptospirose: Diagnóstico e Manejo Clínico/Ministério da Saúde, Secretaria de Vigilância em Saúde.

Brasil. Ministério da Saúde. Boletim epidemiológico. 2021; 42-47. Disponível em: <https://www.gov.br/saude/pt-br/assuntos/saude-de-a-a-z/t/tracoma/publicacoes/boletim-epidemiologico-doencas-tropicais-negligenciadas>. Acesso em 13/06/2023.

Brown, K., & Prescott, J. (2008). Leptospirosis in the family dog: a public health perspective. CMAJ. Canadian Medical Association Journal, 178(4), 399–401. https://doi.org/10.1503/cmaj.071097.

Chacko, C. S., Jayakumar, A., Binu, S. L., Pant, R. D., Giri, A., Chand, S., & Nandakumar, U. P. (2021). A short review on leptospirosis: Clinical manifestations, diagnosis and treatment. Clinical Epidemiology and Global Health, 11, 100741. https://doi.org/10.1016/j.cegh.2021.100741.

Coiro, C. J., Langoni, H., Silva, R. C., & Ullmann, L. S. (2011). Fatores de risco para leptospirose, leishmaniose, neosporose e toxoplasmose em cães domiciliados e peridomíciliados em Botucatu-SP. Veterinária e Zootecnia, 18(3), 393–407.

Collantes, T. M. A., David, J. M. F., Vergara, E. J. S., Armea, S. R. D., & Flores, M. L. S. (2016). Detection of pathogenic leptospires and analysis of factors and clinical signs associated with canine leptospirosis. Philippine Journal of Veterinary and Animal Sciences, 42(1), 41–89.

Day, M. J., Horzinek, M. C., Schultz, R. D., & Squires, R. A. (2016). Diretrizes para a vacinação de cães e gatos. Journal of Small Animal Practice, 57, 699–706.

Esteves, S. B., Santos, C. M., Silva, B. C. S., Salgado, F. F., Guilloux, A. G. A., Cortez, A., Lucco, R. C., & Miotto, B. A. (2023). Time for change? A systematic review with meta-analysis of leptospires infecting dogs to assess vaccine compatibility in Brazil. Preventive Veterinary Medicine, 105869. https://doi.org/10.1016/j.prevetmed.2023.105869.

Goldstein, R. E. (2010). Canine leptospirosis. Veterinary Clinics: Small Animal Practice, 40(6), 1091–1101. https://doi.org/10.1016/j.cvsm.2010.07.008.

Greene, C. E., & Appel, M. J. (2011). Canine distemper. In C. E. Greene (Ed.), Enfermedades infecciosas: Perros y gatos (pp. 25–41). Editora Interamericana.

Hagiwara, M. K. (2003). Leptospirose canina. Boletim técnico de novembro de 2003. Pfizer Saúde Animal, 1, 1-6.

Hagiwara, M. K., Miotto, B. A., Kogika, M. M., Jerico, M. M., Neto, J. P. A., Kogika, M. M. (2015). Tratado de Medicina Interna de Cães e Gatos (1ºed). Roca. Rio de Janeiro, Brasil.

Harvey, J. W. (2012). Veterinary hematology: A diagnostic guide and color atlas. Elsevier Saunders.

Hodgson, D. R., Mckeever, R. H., & McGowan, C. H. (2014). Hematology and biochemistry. Elselvier Saunders.

Jericó, M. M., Andrade Neto, J. P., & Kogika, M. M. (2015). Tratado de medicina interna de cães e gatos. Roca Ltda.

Jubb, K. V. F., Kennedy, P. C., & Palmer, N. (2016). Jubb, Kennedy & Palmer’s Pathology of Domestic Animals: Hematopoietic System; Endocrine Glands; Female Genital System; Male Genital System]. Cardiovascular System (Elsevier, Ed.). Elsevier.

Klosowski, M. L., & Bohn, A. A. (2023). Microscopic detection of Leptospira bacterial organisms in urine sediment from a young dog with leptospirosis and a review of the pathobiology and diagnosis of canine leptospirosis. Veterinary Clinical Pathology, 52(1), 112–118. https://doi.org/10.1111/vcp.13129.

Kogika, M. M., Hagiwara, M. K., & Mirandola, R. M. S. (1990). Alterações bioquímicas na leptospirose canina. Brazilian Journal of Veterinary Research and Animal Science, 27(2), 177–182. https://doi.org/10.11606/issn.0000-0000.272177-182.

Kohn, B., Steinicke, K., Arndt, G., Gruber, A. D., Guerra, B., Jansen, A., Kaser‐Hotz, B., Klopfleisch, R., Lotz, F., & Luge, E. (2010). Pulmonary abnormalities in dogs with leptospirosis. Journal of Veterinary Internal Medicine, 24(6), 1277–1282. https://doi.org/10.1111/j.1939-1676.2010.0585.x.

Langston, C. E., & Heuter, K. J. (2003). Leptospirosis: A re-emerging zoonotic disease. Veterinary Clinics: Small Animal Practice, 33(4), 791–807. https://doi.org/10.1016/S0195-5616(03)00026-3.

Magaldi, A. J., Yasuda, P. N., Kudo, L. H., Seguro, A. C., & Rocha, A. S. (1992). Renal involvement in leptospirosis: a pathophysiologic study. Nephron, 62(3), 332–339. https://doi.org/10.1159/000187069.

Marteli, A. N., Genro, L. V., Diament, D., & Guasselli, L. A. (2020). Análise espacial da leptospirose no Brasil. Saúde Em Debate, 44, 805–817. https://doi.org/10.1590/0103-1104202012616.

McGavin, D., & Zachay, J. F. (2013). Bases da patologia em veterinária. Elsevier Brasil.

Miotto, B. A., Guilloux, A. G. A., Tozzi, B. F., Moreno, L. Z., Hora, A. S., Dias, R. A., Heinemann, M. B., Moreno, A. M., Filho, A. F. S., & Lilenbaum, W. (2018). Prospective study of canine leptospirosis in shelter and stray dog populations: Identification of chronic carriers and different Leptospira species infecting dogs. PloS One, 13(7), e0200384. https://doi.org/10.1371/journal.pone.0200384.

Monahan, A. M., Callanan, J. J., & Nally, J. E. (2009). Host-pathogen interactions in the kidney during chronic leptospirosis. Veterinary Pathology, 46(5), 792–799. https://doi.org/10.1354/vp.08-VP-0265-N-REV.

Morikawa, V. M., Bier, D., Pellizzaro, M., Ullmann, L. S., Paploski, I. A. D., Kikuti, M., Langoni, H., Biondo, A. W., & Molento, M. B. (2015). Seroprevalence and seroincidence of Leptospira infection in dogs during a one-year period in an endemic urban area in Southern Brazil. Revista Da Sociedade Brasileira de Medicina Tropical, 48(1), 50–55. https://doi.org/10.1590/0037-8682-0213-2014.

Nelson, R., & Couto, C. G. (2015). Medicina interna de pequenos animais (3.ed.). Elsevier Brasil.

Ramos, T. M. V., Balassiano, I. T., Silva, T. S. M., & Nogueira, J. M. R. (2022). Leptospirose: Características da enfermidade em humanos e principais técnicas de diagnóstico laboratorial. Revista Brasileira de Análises Clínicas, 53(3), 211–218. https://doi.org/10.21877/2448-3877.202102110.

Richter, K. P. (2005). Doenças do fígado e do sistema hepatobiliar. In T. R. Tams (Ed.), Gastroenterologia de pequenos animais (pp. 283–348). Roca.

Sessions, J. K., & Greene, C. E. (2004). Canine leptospirosis: epidemiology, pathogenesis, and diagnosis. Compendium on Continuing Education for the Practicing Veterinarian, 26(8), 606–624. https://doi.org/10.1111/j.1939-1676.2010.0654.x.

Silva, E. R. D. F. S., Melo, W. G. G., Sousa, M. P., Bezerra, D. O., Gonçalves, L. M. F., & Mineiro, A. L. B. B. (2020). Leptospirose canina: revisão de literatura. Revista Científica de Medicina Veterinária, 34, 1–11.

Silva, R. A., Rodrigues, M. C., Virgens, M. S., Rodrigues, K. F., Souza, F. B., Silva, T. S., & Melo, K. M. S. (2018). Leptospirose canina: Relato de caso. PUBVET, 12(6), 1–6. https://doi.org/10.22256/pubvet.v12n6a102.1-6.

Silva, R. C., Lima, V. Y., Silva, A. V., Souza, L. C., & Langoni, H. (2016). Seroepidemiological survey for canine leptospirosis in the coast of São Paulo State, Brazil. Veterinária e Zootecnia, 23(3), 495–503.

Sistema Integrado de Informações sobre Desastres. Disponível em: <https://s2id.mi.gov.br/páginas/relatórios/> Acesso em: 10/03/2023.

Stockham, S. L., & Scott, M. A. (2011). Fundamentos de patologia clínica veterinária.

Thrall, M. A., Weiser, G., Allison, R. W., & Campbell, T. W. (2022). Veterinary hematology, clinical chemistry, and cytology. John Wiley & Sons.

Tilley, L. P., & Smith Junior, F. W. (2014). Consulta veterinária em 5 minutos. Manole Ltda.

Van de Maele, I., Claus, A., Haesebrouck, F., & Daminet, S. (2008). Leptospirosis in dogs: a review with emphasis on clinical aspects. Veterinary Record, 163(14), 409–413. https://doi.org/10.1136/vr.163.14.409.

Wintrobe, M. M. (1974). Clinical hematology. In Academic Medicine. Lea & Febiger.

Zachary, J. F., McGavin, D., & McGavin, M. D. (2012). Bases da patologia em veterinária. Elsevier Brasil.

Published

2023-08-21

Issue

Section

Medicina veterinária

How to Cite

Canine leptospirosis: A clinical approach and the importance of epidemiological diagnosis in the city of Seropédica, Rio de Janeiro, Brazil. (2023). Pubvet, 17(09), e1446. https://doi.org/10.31533/pubvet.v17n9e1446

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