Oclacitinib in the control of pruritus in atopic patients and other canine dermatopathies: Report of 22 cases

Authors

  • Machado Alves Machado Universidade Federal Rural do Rio de Janeiro
  • Flávia Clare Goulart de Carvalho Clínica SOS animal; Pós-graduação equalis
  • Tábata Massessine Rosas Médica veterinária
  • Natália Lopes Lôres Universidade Federal Rural do Rio de Janeiro
  • Mariana Bezerra Mascarenhas Promove Clínica Veterinária
  • Julio Israel Fernandes Universidade Federal Rural do Rio de Janeiro

DOI:

https://doi.org/10.31533/pubvet.v13n4a281.1-8

Keywords:

dogs, treatment, allergies

Abstract

Interleukin-31 is a cytokine responsible for inducing pruritus by binding to specific receptor in the nervous system. The objective of this study was to evaluate the efficacy of oclacitinib in pruritus control in dogs with pruritic dermatopathies. Twenty-two dogs, males and females that presented pruritus, were randomly selected for diagnosis of pruritic dermatopathies. Assessments were made through visual pruritus scale (VAS). The tutors assessed the degree of pruritus, scoring 0-10 before the drug, 4 hours after, 24 hours after and 4, 7, 14, 15, 21 and 28 days after starting treatment. The study achieved efficacy of 67% after 28 days. It is concluded that clactinib has shown to be effective and rapid, inhibited pruritus stimulation in all dermatopathies studied, thus it can be used in diseases with secondary or primary pruritus.

Published

2019-04-12

Issue

Section

Medicina veterinária

How to Cite

Oclacitinib in the control of pruritus in atopic patients and other canine dermatopathies: Report of 22 cases. (2019). Pubvet, 13(04). https://doi.org/10.31533/pubvet.v13n4a281.1-8

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