Platelet-rich fibrin in the veterinary surgical clinic
Review
DOI:
https://doi.org/10.31533/pubvet.v19n01e1708Keywords:
Dog, veterinary surgical clinic, platelet-rich fibrin, catAbstract
Platelet-rich fibrin (PRF) is a blood product that is part of the second generation of platelet concentrates, being a platelet-derived product (PDP’s), a technique initiated more than 60 years ago. It is a type of regenerative medicine that originated in Human Medicine, but can also be used in Veterinary Medicine, such as in reconstructive surgery. PRF is a biomaterial with tissue regenerative potential, which occurs because it contains high concentrations of growth factors, cytokines and leukocyte platelet content, acting in healing, wound closure and enabling angiogenesis and osteogenesis. The objective of this review was to provide current information on the use of PRF in Veterinary Medicine, in addition to its applicability related to the execution of the technique, the need for equipment and economic aspects. In the literature review carried out, publications from the last fifteen years were analyzed, but pre-existing initial works were also evaluated. The autologous or xenologous use of PRF in corneal lesions has been cited, both in dogs and cats. The use of PDPs in dogs with corneal lesions showed satisfactory results according to the literature and in cats it was reported as a good alternative in the treatment of deep corneal ulcers. Other applications were mainly in skin injuries and bone healing, in addition to a report of successful surgical repair of chronic oronasal fistula.
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