Risks and benefits of early neutering in dogs
Review
DOI:
https://doi.org/10.31533/pubvet.v18n12e1700Keywords:
Early neutering, joint injuries, hip dysplasia, mammary tumorsAbstract
Early neutering in dogs is a common practice initially aimed at population control and the prevention of behavioral and health issues. The literature suggests that neutering performed before the first year of age may be associated with significant health risks for the animals. Studies show that early neutering can increase the propensity for joint injuries, such as hip dysplasia and cranial cruciate ligament rupture, particularly in larger dogs and certain breeds. Additionally, there is evidence that neutering may elevate the risk of various types of cancer, including hemangiosarcoma, lymphoma, mast cell tumors and osteosarcoma, with the age of neutering and the dog's sex being critical factors in the development of these conditions. In contrast, early spaying of females has shown to be effective in reducing the risk of mammary tumors, especially when performed before the first or second estrous cycle. However, early neutering may also increase the risk of urinary incontinence in females, necessitating appropriate management and treatment strategies. Behaviorally, neutering can lead to improvements in issues such as urine marking, mounting and escaping, particularly in male dogs. This article discusses the importance of carefully evaluating the optimal timing for neutering, considering each dog's specific characteristics and the potential risks and benefits associated with the procedure.
References
Beach, F. A. (1970). Coital behavior in dogs: VI. Long-term effects of castration upon mating in the male. Journal of Comparative and Physiological Psychology, 70(3 PART 2), 1–32. https://doi.org/10.1037/h0028711.
Belanger, J. M., Bellumori, T. P., Bannasch, D. L., Famula, T. R., & Oberbauer, A. M. (2017). Correlation of neuter status and expression of heritable disorders. Canine Genetics and Epidemiology, 4(1). https://doi.org/10.1186/s40575-017-0044-6.
Choong, S. S., Mohamad, M. A., Tan, L. P., & Hamdan, R. H. (2021). The predicament of macaque conservation in Malaysia. In Managing Wildlife in a Changing World. https://doi.org/10.5772/intechopen.101136.
Costa, R. E. P., Kinsman, R. H., Owczarczak-Garstecka, S. C., Casey, R. A., Tasker, S., Knowles, T. G., Woodward, J. L., Lord, M. S., & Murray, J. K. (2022). Age of sexual maturity and factors associated with neutering dogs in the UK and the Republic of Ireland. Veterinary Record, 191(6). https://doi.org/10.1002/vetr.1265
Diao, H., Cheng, N., Zhao, Y., Xu, H., Dong, H., Thamm, D. H., Zhang, D., & Lin, D. (2019). Ivermectin inhibits canine mammary tumor growth by regulating cell cycle progression and WNT signaling. BMC Veterinary Research, 15(1). https://doi.org/10.1186/s12917-019-2026-2.
Dorn, M., & Seath, I. J. (2018). Neuter status as a risk factor for canine intervertebral disc herniation (IVDH) in dachshunds: A retrospective cohort study. Canine Genetics and Epidemiology, 5(1). https://doi.org/10.1186/s40575-018-0067-7.
Ferreira, C. C. M., Gomes, L. G., Menezes, S. G., Lobo, P. M., Lima, L. F. S., Pizzinatto, F. D., Campos, C. G., Colodel, E. M., & Souza, R. L. (2023). Patient-specific testicular prosthesis prototype produced with polylactic acid and coated with cyanoacrylate or polymethylmethacrylate. Observatório de la Economia Latinoamericano, 21(6), 5151. https://doi.org/10.55905/oelv21n6-103.
Graves, J. L., McKenzie, B. A., Koch, Z., Naka, A., Spofford, N., & Morrison, J. (2023). Body weight, gonadectomy, and other risk factors for diagnosis of osteoarthritis in companion dogs. Frontiers in Veterinary Science, 10. https://doi.org/10.3389/fvets.2023.1275964.
Hart, B. L., Hart, L. A., Thigpen, A. P., & Willits, N. H. (2020). Assisting decision-making on age of neutering for 35 breeds of dogs: Associated joint disorders, cancers, and urinary incontinence. Frontiers in Veterinary Science, 7. https://doi.org/10.3389/fvets.2020.00388.
Hart, L. A., & Hart, B. L. (2021). An ancient practice but a new paradigm: Personal choice for the age to spay or neuter a dog. Frontiers in Veterinary Science, 8. https://doi.org/10.3389/fvets.2021.603257.
Jacobson, E., Meler, E. N., Delisser, P. J., & Thompson, A. L. (2022). Cystoscopic-guided scissor transection of intramural ectopic ureters as a novel alternate minimally invasive treatment option to laser ablation in female dogs: 8 cases (2011-2020). Journal of the American Veterinary Medical Association, 260(S2), S12–S20. https://doi.org/10.2460/javma.21.03.0153.
Joonè, C. J., & Konovalov, D. A. (2023). The effect of neuter status on longevity in the Rottweiler dog. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-45128-w.
Kriese, M., Kuźniewska, E., Gugołek, A., & Strychalski, J. (2022). Reasons for and behavioral consequences of male dog castration—A questionnaire study in Poland. Animals, 12(15), 1883. https://doi.org/10.3390/ani12151883.
McGreevy, P. D., Thomson, P. C., Pride, C., Fawcett, A., Grassi, T., & Jones, B. (2005). Prevalence of obesity in dogs examined by Australian veterinary practices and the risk factors involved. Veterinary Record, 156(22). https://doi.org/10.1136/vr.156.22.695.
McKenzie, B. (2010). Evaluating the benefits and risks of neutering dogs and cats. In CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources (Vol. 5, pp. 1–18). https://doi.org/10.1079/PAVSNNR20105045.
Mondes, P. H. L., & Tamura, E. K. (2022). Melatonina em animais de companhia: Uma revisão de literatura. Ensaios e Ciência C Biológicas Agrárias e Da Saúde, 25(5-esp). https://doi.org/10.17921/1415-6938.2021v25n5-espp671-681.
Oberbauer, A. M., Belanger, J. M., & Famula, T. R. (2019). A review of the impact of neuter status on expression of inherited conditions in dogs. In Frontiers in Veterinary Science (Vol. 6, p. 560). https://doi.org/10.3389/fvets.2019.00397.
Overley, B., Shofer, F. S., Goldschmidt, M. H., Sherer, D., & Sorenmo, K. U. (2005). Association between ovarihysterectomy and feline mammary carcinoma. Journal of Veterinary Internal Medicine, 19(4), 560–563. https://doi.org/10.1892/0891-6640(2005)19 [560: ABOAFM]2.0.CO;2.
Pegram, C., O’Neill, D. G., Church, D. B., Hall, J., Owen, L., & Brodbelt, D. C. (2019). Spaying and urinary incontinence in bitches under UK primary veterinary care: a case–control study. Journal of Small Animal Practice, 60(7), 560. https://doi.org/10.1111/jsap.13014.
Poss, J. E., & Bader, J. O. (2008). Results of a free spay/neuter program in a hispanic colonia on the Texas-Mexico border. Journal of Applied Animal Welfare Science, 11(4), 346–351. https://doi.org/10.1080/10888700802330010.
Rawlings, C. A., Coates, J. R., Purinton, P. T., Barsanti, J. A., Carlisle, A., & Oliver, J. E. (2005). Evaluation of a selective neurectomy model for low urethral pressure incontinence in female dogs. American Journal of Veterinary Research, 66(4), 695–699. https://doi.org/10.2460/ajvr.2005.66.695.
Silva, T. C., Bassoli, A. G., Queiroz Júnior, J. P., Ferreira-Silva, J. C., Aleixo, G. A. S., & Andrade, M. B. (2015). Castração pediátrica em cães e gatos: Revisão da literature. In Medicina Veterinaria (Brazil) (Vol. 9, Issues 1–4, pp. 20–25).
Silveira, V. C. A., Colla, A. C. N., & Mestieri, M. L. A. (2021). Castração química em pequenos animais: Onde estamos? PUBVET, 15(3), 1–7. https://doi.org/10.31533/pubvet.v15n03a762.1-7.
Sorenmo, K. U., Durham, A. C., Radaelli, E., Kristiansen, V., Peña, L., Goldschmidt, M. H., & Stefanovski, D. (2019). The estrogen effect: Clinical and histopathological evidence of dichotomous influences in dogs with spontaneous mammary carcinomas. PLoS ONE, 14(10), e0224504. https://doi.org/10.1371/journal.pone.0224504.
Souza, M. V., Pandolfi, I. A., Santos, R. M., Júnior, D. P., & Paulino Júnior, D. (2019). Levantamento de dados e causas de eutanásia em cães e gatos: avaliação ética-moral. PUBVET, 13(11), 1–13. https://doi.org/10.31533/pubvet.v13n11a451.1-13.
Sundburg, C. R., Belanger, J. M., Bannasch, D. L., Famula, T. R., & Oberbauer, A. M. (2016). Gonadectomy effects on the risk of immune disorders in the dog: a retrospective study. BMC Veterinary Research, 12(1), 278. https://doi.org/http://dx.doi.org/10.1186/s12917-016-0911-5.
Thornton, L. A., Burchell, R. K., Burton, S. E., Lopez-Villalobos, N., Pereira, D., MacEwan, I., Fang, C., Hatmodjo, A. C., Nelson, M. A., Grinberg, A., Velathanthiri, N., & Gal, A. (2018). The effect of urine concentration and pH on the growth of Escherichia coli in canine urine in vitro. Journal of Veterinary Internal Medicine, 32(2), 752–756. https://doi.org/10.1111/jvim.15045.
Trapp, S. M., Iacuzio, A. I., Junior, F. A. B., Kemper, B., Silva, L. C., Okano, W., Tanaka, N. M., Grecco, F. C. de A. R., Cunha Filho, L. F. C., & Sterza, F. A. M. (2010). Causas de óbito e razões para eutanásia em uma população hospitalar de cães e gatos. Brazilian Journal of Veterinary Research and Animal Science, 47(5), 395–402.
Vazquez, E., Lipovka, Y., Cervantes-Arias, A., Garibay-Escobar, A., Haby, M. M., Queiroga, F. L., & Velazquez, C. (2023). Canine mammary cancer: State of the art and future perspectives. In Animals (Vol. 13, Issue 19, p. 3147). https://doi.org/10.3390/ani13193147.
Veronesi, M. C., Rota, A., Battocchio, M., Faustini, M., & Mollo, A. (2009). Spaying-related urinary incontinence and oestrogen therapy in the bitch. Acta Veterinaria Hungarica, 57(1), 171–182. https://doi.org/10.1556/AVet.57.2009.1.17.
Yeom, J., Cho, Y., Ahn, S., & Jeung, S. (2023). Anticancer effects of alpelisib on PIK3CA-mutated canine mammary tumor cell lines. Frontiers in Veterinary Science, 10. https://doi.org/10.3389/fvets.2023.1279535.
Žák, J., Voslářová, E., Večerek, V., & Bedáňová, I. (2015). Sex, age and size as factors affecting the length of stay of dogs in Czech shelters. Acta Veterinaria Brno, 84(4), 407–413. https://doi.org/10.2754/avb201584040407.
Zedan, I. A., & Al-Badrany, M. S. (2021). Control of stray dog population by single intratesticular injection of tannic acid. Iraqi Journal of Veterinary Sciences, 35, 33–36. https://doi.org/10.33899/IJVS.2021.130454.1826.
Zlotnick, M., Corrigan, V., Griffin, E., Alayon, M., & Hungerford, L. (2019). Incidence of health and behavior problems in service dog candidates neutered at various ages. Frontiers in Veterinary Science, 6. https://doi.org/10.3389/fvets.2019.00334.
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