Visceral analgesia with continuous infusion of maropitant in bitches undergoing ovarian salpingohysterectomy
DOI:
https://doi.org/10.31533/pubvet.v17n13e1515Keywords:
dogs, infusion, maropitant, ovariosalpingohisterectomyAbstract
Maropitant is used in dogs and cats as an antiemetic, with its antagonistic action being on NK-1 receptors, and its closest ligand being the neuropeptide known as substance P, which plays a primary role in the transmission and maintenance of nociceptive information. Thus, inhibiting the release of this substance is considered a conduit to effective analgesia. The objective of this work was to evaluate the analgesic efficacy of maropitant in two bitches undergoing ovarian salpingohysterectomy
References
Alvillar, B. M., Boscan, P., Mama, K. R., Ferreira, T. H., Congdon, J., & Twedt, D. C. (2012). Effect of epidural and intravenous use of the neurokinin-1 (NK-1) receptor antagonist maropitant on the sevoflurane minimum alveolar concentration (MAC) in dogs. Veterinary Anaesthesia and Analgesia, 39(2), 201–205. https://doi.org/10.1111/j.1467-2995.2011.00670.x.
Bednarski, R., Grimm, K., Harvey, R., Lukasik, V. M., Penn, W. S., Sargent, B., & Spelts, K. (2011). AAHA anesthesia guidelines for dogs and cats. Journal of the American Animal Hospital Association, 47(6), 377–385.
Benchaoui, H. A., Cox, S. R., Schneider, R. P., Boucher, J. F., & Clemence, R. G. (2007). The pharmacokinetics of maropitant, a novel neurokinin type‐1 receptor antagonist, in dogs. Journal of Veterinary Pharmacology and Therapeutics, 30(4), 336–344. https://doi.org/10.1111/j.1365-2885.2007.00877.x.
Boscan, P., Monnet, E., Mama, K., Twedt, D. C., Congdon, J., & Steffey, E. P. (2011). Effect of maropitant, a neurokinin 1 receptor antagonist, on anesthetic requirements during noxious visceral stimulation of the ovary in dogs. American Journal of Veterinary Research, 72(12), 1576–1579. https://doi.org/10.2460/ajvr.72.12.1576.
Diemunsch, P., & Grélot, L. (2000). Potential of substance P antagonists as antiemetics. Drugs, 60, 533–546. https://doi.org/10.2165/00003495-200060030-00002.
Favaretto, A. F., Mastrocinque, S., Macedo, J. S., & Rossetti, R. (2022). Maropitant ou cetamina para o controle da dor em cadelas submetidas à ovariohisterectomia. PUBVET, 16(5), 1–8. https://doi.org/10.31533/pubvet.v16n05a1111.1-8.
Garcia, C., Borges, I. S., Padilha, V. S., Valau, A., & Vargas, D. (2021). Avaliação do efeito analgésico do maropitant em gatas submetidas à ovariohisterectomia eletiva. PUBVET, 15(3), 1–7. https://doi.org/10.31533/pubvet.v15n03a772.1-7.
Grimm, K. A., Lamont, L. A., Tranquilli, W. J., Greene, S. A., & Robertson, S. A. (2015). Veterinary anesthesia and analgesia. John Wiley & Sons.
Harrison, S., & Geppetti, P. (2001). Substance p. The International Journal of Biochemistry & Cell Biology, 33(6), 555–576. https://doi.org/10.1016/S1357-2725(01)00031-0.
Kraus, B. L. H. (2017). Spotlight on the perioperative use of maropitant citrate. Veterinary Medicine: Research and Reports, 8, 41–51. https://doi.org/10.2147/vmrr.s126469.
Laird, J. M. A., Olivar, T., Roza, C., Felipe, C., Hunt, S. P., & Cervero, F. (2000). Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene. Neuroscience, 98(2), 345–352. https://doi.org/10.1016/S0306-4522(00)00148-2.
Lumb, W. V, Jones, E. W., Téllez, E., & Retana, R. (2017). Anestesia veterinaria. Continental.
Marquez, M., Boscan, P., Weir, H., Vogel, P., & Twedt, D. C. (2015). Comparison of nk-1 receptor antagonist (maropitant) to morphine as a pre-anaesthetic agent for canine ovariohysterectomy. PLoS One, 10(10), e0140734. https://doi.org/10.1371/journal.pone.0140734.
Muir, W. W., & Hubbell, J. A. E. (2001). Manual de anestesia veterinária. Artmed Editora.
Puente‐Redondo, V. A., Siedek, E. M., Benchaoui, H. A., Tilt, N., Rowan, T. G., & Clemence, R. G. (2007). The anti‐emetic efficacy of maropitant (CereniaTM) in the treatment of ongoing emesis caused by a wide range of underlying clinical aetiologies in canine patients in Europe. Journal of Small Animal Practice, 48(2), 93–98. https://doi.org/10.1111/j.1748-5827.2006.00321.x.
Ruggieri, M. R., Filer-Maerten, S., Hieble, J. P., & Hay, D. W. P. (2000). Role of neurokinin receptors in the behavioral effect of intravesical antigen infusion in guinea pig bladder. The Journal of Urology, 164(1), 197–202. https://doi.org/10.1016/S0022-5347(05)67494-0.
Tranquilli, W. J., Thurmon, J. C., & Grimm, K. A. (2d013). Lumb and Jones’ veterinary anesthesia and analgesia. John Wiley & Sons.
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