Chronic lymphocytic leukemia in puppy: Case report

Authors

  • Carolina Ferreira de Oliveira Universidade Federal de Alagoas https://orcid.org/0000-0003-2985-6745
  • Thamires de Oliveira Soares Universidade Federal de Alagoas
  • Daniel Acioli Tenório Universidade Federal de Alagoas
  • José Jefferson Ramos Farias Médico Veterinário Anestesiologista Volante, Maceió
  • Carla Fabiana Gomes de Jesus Secretaria Municipal de Saúde de Itabaiana, Sergipe

DOI:

https://doi.org/10.31533/pubvet.v17n11e1472

Keywords:

hematopoietic cells, diagnosis, neoplasia, hematopoietic cells, diagnosis, neoplasia

Abstract

As a disease with cellular variability that affects both dogs and cats of various breeds, sizes and ages, despite being considered a rare disease, leukemia can be hidden and not present in routine clinical or hematological analyses, making it necessary to carry out repetitive complementary exams to identify neoplastic changes in hematopoietic cells, which is evidenced in that the physical examination and anamnesis of the reported case of Chronic Lymphocytic Leukemia (CLL) pointed to other suspicions, proving that half of all cases of CLL can be asymptomatic and accidentally identified after evaluating the hematological profile. Thus, the diagnosis was given through information obtained via a review of the medical record, interview with the animal's owner and reiteration of the analysis methods to which the patient was submitted. This highlights the relevance of the association of anamnesis, physical examination, diagnostic hypothesis and auxiliary tests to identify the abnormality and define the right treatment, since leukemias are often misinterpreted and mistaken for other diseases, even with other types of neoplasia, thus being susceptible to inadequate therapeutic resources.

References

Alencar, N. X., Meneses, A. M. C., Kohayagawa, A., Takahira, R. K., & Sequeira, J. L. (2008). Leucemia linfocítica crônica em cão: relato de caso. Revista Brasileira de Ciência Veterinária, 15(3). https://doi.org/10.4322/rbcv.2014.219.

Alves, M., Conti, L., Andrade Júnior, P., & Donatele, D. (2015). Leucemia viral felina: Revisão. PUBVET, 9(2), 86–100. https://doi.org/10.22256/pubvet.v9n2.86-100.

Anjos, A. R., Silva, M. A., & Borelli, P. (2000). Matriz extracelular e leucemia. Revista Brasileira de Hematologia e Hemoterapia, 22, 404–412. https://doi.org/10.1590/s1516-84842000000300007.

Carmichael, K. P., Bienzle, D., & McDonnell, J. J. (2002). Feline leukemia virus-associated myelopathy in cats. Veterinary Pathology, 39(5), 536–545.

Cruppi, C. C. (2018). Leucemia linfocítica crônica em cães: Revisão de literatura e relato de caso. Universidade Brasil.

Daleck, C. R., Fonseca, C. S., & Canola, J. C. (2016). Oncologia em cães e gatos. Roca.

Fraga, H. E. J. (2006). Leucemia linfocítica crônica: uma breve revisão. Universidade Federal de Santa Maria.

Hamerschlak, N. (2008). Leucemias e linfomas. In Temas em psico-oncologia (Vol. 1). Sumus.

Leifer, C. E., & Matus, R. E. (1985). Lymphoid leukemia in the dog: Acute lymphoblastic leukemia and chronic lymphocytic leukemia. Veterinary Clinics of North America: Small Animal Practice, 15(4), 723–739. https://doi.org/10.1016/s0195-5616(85)50032-7.

Lemos, M., Oliveira, J. S., Almeida, S. J., Oliveira, P. G. de, Ferraz, H. T., Lopes, D. T., Saturnino, K. C., Borges, K. I. N., Ramos, D. G. de S., & Braga, Í. A. (2019). Ocorrência da leucemia felina e imunodeficiência felina em gatos domésticos do município de Mineiros, Goiás. PUBVET, 13(3), 1–7. https://doi.org/10.31533/pubvet.v13n3a283.1-7

Morris, J., & Dobson, J. M. (2001). Small animal oncology. Wiley Online Library.

Reya, T., Morrison, S. J., Clarke, M. F., & Weissman, I. L. (2001). Stem cells, cancer, and cancer stem cells. Nature, 414(6859), 105–111. https://doi.org/10.1038/35102167.

Safran, N., Perk, K., Eyal, O., & Dahlberg, J. E. (1992). Isolation and preliminary characterisation of a novel retrovirus isolated from a leukaemic dog. Research in Veterinary Science, 52(2), 250–255. https://doi.org/10.1016/0034-5288(92)90018-w.

Silva, D. H. L., Barbosa, B. C., Horta, R. S., & Leme, F. O. P. (2018). Importância do vírus da leucemia felina na linfomagênese: Revisão. PUBVET, 12(11), 1–8. https://doi.org/10.31533/pubvet.v12n11a207.1-8.

Thrall, M. A.; Weiser, G. A.; Robin, W. C. & Terry, W. (2022). Veterinary hematology, clinical chemistry, and cytology.

Vicente Sobrinho, L. S., Vides, J. P., Braga, E. T., Gomes, A. D., Rossi, C. N., & Marcondes, M. (2011). Sorofrequência de infecção pelo vírus da imunodeficiência felina e vírus da leucemia felina em gatos do município de Araçatuba, São Paulo. Brazilian Journal of Veterinary Research and Animal Science, 48(5), 378–383.

Published

2023-11-09

Issue

Section

Medicina veterinária

How to Cite

Chronic lymphocytic leukemia in puppy: Case report. (2023). Pubvet, 17(11), e1472. https://doi.org/10.31533/pubvet.v17n11e1472