Transmissible venereal tumor observed in population control at the municipality of Salinas, North of Minas Gerais

Authors

DOI:

https://doi.org/10.31533/pubvet.v17n8e1440

Keywords:

células redondas, neoplasma, nódulo, tumor de Sticker

Abstract

Transmissible venereal tumor (TVT) is also known as Sticker tumor, canine condyloma or venereal lymphosarcoma, referred to as a contagious neoplasm, consisting of round cells, primarily found in the external genitalia, but extragenital and metastatic primary neoplasms may also occur. They can be single or multiple, up to 10 cm in diameter, with a reddish, ulcerated surface and multiple nodules. This work proposes to carry out a survey of transmissible venereal tumors observed in the population control project in the municipality of Salinas, North of Minas Gerais. The research was carried out at the IFNMG Veterinary Hospital, Salinas Campus, MG, with 31 dogs from Salinas’s municipal shelter, from July to December 2022. Vaginal or penile swab and imprint techniques were performed on the dogs. The frequency of TVT in the evaluated dogs was 54.84%. Of the 17 animals positive for TVT, only 3 of them (17.65%) had macroscopic lesions with neoplastic masses present in the genital region, while the other 14 (82.35%) did not. Based on the cytomorphological tests, the highest frequency was of the plasmacytoid type of TVT, with 64.70%. According to the distribution by sex, evaluating in general, there was a higher frequency of TVT in females (64.70%) compared to males (35.30%). However, the greater number of animals participating in the project in this period was female, with 22 females and 9 males. Regarding the frequency of TVT distributed according to sex in terms of the cytomorphology of tumor cells, a higher frequency of plasmacytoid TVT was evaluated in both females (63.64%) and males (66.66%). The present study is the first to carry out a survey of TVT cases in dogs in the municipality of Salinas, North of Minas Gerais, and the data obtained suggest high incidence, in addition to affecting both sexes. One of the factors that favor the spread of TVT is the lack of information regarding animal care, responsible tutorship and castration projects, preventing the spread not only of TVT, but also other public health diseases, with guidance to the community being extremely important. We propose to carry out new municipal or regional studies in order to compare the occurrences of TVT, since the culture of the region still is to keep its animals semi-indoors, and there is a large number of stray dogs, thus justifying the data found.

References

Arcila-Villa, A., Dussán-Lubert, C., & Pedraza-Ordoñez, F. (2018). Distribution and prevalence of transmissible venereal tumor in the Colombian canine population. Revista Colombiana de Ciencias Pecuarias, 31(3), 180–187. https://doi.org/10.17533/udea.rccp.v31n3a02.

Barbosa, D. S., Milhomem, K. M. G., Carvalho, P. V. S., & Macedo, A. A. (2022). Tumor venéreo transmissível canino - Relato de caso. Revista Sustinere, 10, 60–67. https://doi.org/10.12957/sustinere.2022.65858

Birhan, G., & Chanie, M. (2015). A review on canine transmissible venereal tumor: from morphologic to biochemical and molecular diagnosis. Academic Journal of Animal Diseases, 4(3), 185–195.

Campos, C. P. A., Porto, C. D., Manhoso, F. F. R., Hataka, A., & Palombarini, A. T. (2017). Aspectos epidemiológicos do tumor venéreo transmissível no município de Marília - SP no período de 2011 a 2012. Revista Unimar Ciências, 22(1–2).

Costa, M. (2008). Tumor venéreo transmissível canino. In C. R. Daleck, A. B. Nardi, & S. Rodaski (Eds.), Oncologia em cães e gatos. Roca, Brasil.

Crossley, R., & Ramírez, J. A. (2017). Tumor venéreo transmisible canino de presentación atípica. Revista de La Facultad de Medicina Veterinaria y de Zootecnia, 64(3), 78–90. https://doi.org/10.15446/rfmvz.v64n3.68695.

Cruz, G. D., Santos, C. F., Santos, C. R., Uschi, C. S., Elias, T., Xavier, J. G., Bonamin, L. V, & Villano, L. (2012). Metástase visceral de tumor venéreo transmissível em cão. Veterinária e Zootecnia, 16(3), 465–470.

Daleck, C. R., De Nardi, A. B., Rodigheri, S. M., & Motta, F. R. (2008). Neoplasia do sistema urinário. In Oncologia em cães e gatos (Vol. 1). Roca.

Daleck, C. R., Fonseca, C. S., & Canola, J. C. (2016). Oncologia em cães e gatos. Roca.

Fonseca, F. M. C., Castro, G. N., Ribeiro, M. C., Stefanine, N. R., Moura, L. T. S., & Javaé, N. R. K. (2017). Incidência de tumor venéreo transmissível em caninos. Revista Científica de Medicina Veterinária, 14(28), 1–9.

Fonseca, L. S., Silva, S. M. M. S., Rocha Neto, H. J., Horta, R. S., Quessada, A. M., & Miranda, D. F. H. (2014). Tumor venéreo transmissível (TVT) com metástase para a glândula mamária. Acta Scientiae Veterinariae, 42, 1–6.

Horta, A. C. L., Batista, A. C. S., Souza, A. M., Quintas, D. A., Costa, G. C. S., Wanzeler, J. V. F., Martins, M. F. S., & Cunha, T. V. (2020). Tumor venéreo transmissível nasal em cão: Relato de caso. Brazilian Journal of Development, 8(1), 351–355. https://doi.org/10.34117/bjdv8n1-494.

Huppes, R. R., Silva, C. G., Uscategui, R. A. R., De Nardi, A. B., Souza, F. W., Costa, M. T., Amorim, R. L., Pazzini, J. M., & Faria, J. L. M. (2014). Tumor venéreo trasmissível (TVT): Estudo retrospectivo de 144 casos. Ars Veterinaria, 30(1), 13–18. https://doi.org/10.15361/2175-0106.2014v30n1p13-18.

Lira, T. L., Brito, E. C. P. M., Barros, B. S., Burns, L. V., Passos, A. C. B. T., & Souza, P. M. (2022). Tumor venéreo transmissível cutâneo: Relato de casos. PUBVET, 16(12), 1–9. https://doi.org/10.31533/pubvet.v16n12a1288.1-9.

Murchison, E. P. (2009). Clonally transmissible cancers in dogs and Tasmanian devils. Oncogene, 27(S2), S19. https://doi.org/10.1038/onc.2009.350

Ostrander, E. A., Davis, B. W., & Ostrander, G. K. (2016). Transmissible tumors: breaking the cancer paradigm. Trends in Genetics, 32(1), 1–15. https://doi.org/10.1016/j.tig.2015.10.001.

Paranzini, C. S., Santanna, M. C., Santis, G. W., & Martins, M. I. M. (2015). Prevalência dos diferentes tipos morfológicos de tumor venéreo transmissível e a associação com o prognóstico dos cães tratados com sulfato de vincristina: estudo retrospectivo. Semina Ciências Agrárias, 36(6), 3795–3800. https://doi.org/1679-0359.2015v36n6p3795.

Pedrozo, C. S., Abreu, L. B., Silva, P. E. V., Menegatti, R. L. M., & Melo, C. M. F. (2023). Estudo retrospectivo de tumor venéreo transmissível em cães na cidade de Dourados, Mato Grosso do Sul. PUBVET, 17(2), 1–6. https://doi.org/10.31533/pubvet.v17n02a1342.

Peixoto, P. V., Teixeira, R. S., Mascarenhas, M. B., França, T. N., Azevedo, S. C. S., Reinacher, M., Costa, T. S., & Ramadinha, R. R. (2016). Formas atípicas e aspectos clínico-epidemiológicos do tumor venéreo transmissível canino no Brasil. Brazilian Journal of Veterinary Medicine, 38(Supl. 2), 101–107.

Regiani, M. Z., & Vasconcellos, M. (2018). Tumor venéreo transmissível canino. A mais antiga linhagem clonal conhecida na natureza Canine transmissible venereal tumor. PUBVET, 12(3), 1–5. https://doi.org/10.22256/pubvet.v12n3a41.1-5

Santos, D. E., Silva, D. T., Toledo-Pinto, E. A., & Lot, R. F. E. (2008). Tumor venéreo transmissível (TVT): Revisão de literatura. Revista Científica Eletrônica de Medicina Veterinária, 110(4), 1–7.

Siddle, H. V, & Kaufman, J. (2013). A tale of two tumours: comparison of the immune escape strategies of contagious cancers. Molecular Immunology, 55(2), 190–193. https://doi.org/10.1016/j.molimm.2012.10.017

Siddle, H. V, & Kaufman, J. (2015). Immunology of naturally transmissible tumours. Immunology, 144(1), 11–20. https://doi.org/10.1111/imm.12377.

Silva, R. S., Jank, J. A., Torres, S. S., Angst, J. P. S., Wolkmer, P., Brendler, S., Rossato, C. K., & Dornelles, G. L. (2020). Diagnósticos citológicos de tumor venéreo transmissível (TVT) na região de Cruz Alta/RS: estudo retrospectivo. Brazilian Journal of Development, 6(12), 94205–94215. https://doi.org/10.34117/bjdv6n12-040.

Silva, A. C. da. (2022). Tumor venéreo transmissível (TVT) em canino: relato de caso. 50 f. TCC (Graduação) - Curso de Medicina Veterinária, Universidade Federal Rural de Pernambuco, Recife.

Sreekumar, K. S., Narendran, P. V, & Ajidhan, V. B. (2015). Case Study of Canine Transmissible Venereal Tumor. EC Veterinary Science, 2(2015), 109–117. https://doi.org/10.35172/rvz.2020.v27.495.

Valençoela, R. A., Antunes, T. R., Sorgatto, S., Oliveira, B. B., Godoy, K. C. S., & Souza, A. I. (2015). Aspectos citomorfológicos e frequência dos subtipos de tumor venéreo transmissível canino no município de campo grande, ms, Brasil. Acta Veterinaria Brasilica, 9(1), 82–86.

Published

2023-08-17

Issue

Section

Medicina veterinária

How to Cite

Transmissible venereal tumor observed in population control at the municipality of Salinas, North of Minas Gerais. (2023). Pubvet, 17(08), e1440. https://doi.org/10.31533/pubvet.v17n8e1440