Microneedling associated with orchiectomy as a treatment for alopecia x in a German Spitz dog

Authors

  • Fernanda Letícia de Aguiar Mello Universidade Federal da Bahia https://orcid.org/0000-0002-1524-9381
  • Virgínia Paula Couto Vigas Sodré Universidade Federal da Bahia
  • Humberto Santos da Silva Universidade Federal da Bahia
  • Antônio Fernando Uzêda Sodré Universidade Federal da Bahia

DOI:

https://doi.org/10.31533/pubvet.v16n11a1264.1-9

Keywords:

Alopecia, canine, skin disease, hair follicle

Abstract

This study aims to report the case of a male German Spitz canine patient and to present the therapeutic approach of choice: microneedling associated with orchiectomy. Alopecia “X” is a common non-inflammatory and non-pruritic skin disease. In it, there is a racial and age predilection, since it most commonly affects double-coated animals of Nordic breeds, especially German Spitz dogs, between one and five years of age. It is characterized by gradual hair loss, sparing only the head and final thirds of the limbs in its more evolved stages. The etiology and pathogenesis of alopecia X still remain unknown, but there is evidence to genetic factors linked to this disease.

References

Adamo, I. D. (2018). Alopecia x: uma revisão de literatura. Universidade de Santo Amaro.

Baptista, A. B. M. V. (2017). Sinalização e desenvolvimento da Alopecia X em 171 cães da raça Spitz Alemão. Anais Do III Congresso Internacional Da Associação Brasileira de Endocrinologia Veterinária.

Bastos, R. S. C., Farias, K. M., Lopes, C. E. B., Pacheco, A. C. L., & Araújo Viana, D. (2017). Estudo retrospectivo de neoplasias cutâneas em cães da região metropolitana de Fortaleza. Revista Brasileira de Higiene e Sanidade Animal, 11(1), 39–53.

Brunner, M. A. T., Jagannathan, V., Waluk, D. P., Roosje, P., Linek, M., Panakova, L., Leeb, T., Wiener, D. J., & Welle, M. M. (2017). Novel insights into the pathways regulating the canine hair cycle and their deregulation in alopecia X. PloS One, 12(10). https://doi.org/10.1371/journal.pone.0186469.

Cerundolo, R., Bensignor, E., & Guaguére, E. (2008). Sex hormone dermatoses. In E. Guaguére, P. Prélaud, & M. E. Craig (Eds.), A pratical guide in canine dermatology. Merial.

Cerundolo, R., Lloyd, D. H., Persechino, A., Evans, H., & Cauvin, A. (2004). Treatment of canine Alopecia X with trilostane. Veterinary Dermatology, 15(5), 285–293.

Feldman, E. C., Nelson, R. W., Reusch, C., & Scott-Moncrieff, J. C. (2014). Canine and feline endocrinology. Elsevier Health Sciences.

Ferreira, R. R., Silva, M. L., Aguiar, J., Spanamberg, A., Bianchi, S. P., Oliveira, E. C., & Driemeier, D. (2007). Displasias foliculares ligadas à cor da pelagem em cães: displasia folicular dos pêlos pretos e alopecia por diluição da cor. Acta Scientiae Veterinariae, 35(1), 119–124.

Frank, L.A. (2013). Endocrine and metabolic diseases. In W.H. Miller, C. E. Griffin, & K. L. Campbel (Eds.), Muller & Kirk’s small animal dermatology (7th ed.). Elselvier Saunders.

Frank, L.A., Hnilica, K. A., & Oliver, J. W. (2004). Adrenal steroid hormone concentrations in dogs with hair cycle arrest (Alopecia X) before and during treatment with melatonin and mitotane. Veterinary Dermatology, 15(5), 278–284. https://doi.org/https://doi.org/10.1111/j.1365-3164. 2004.00372.x.

Frank, L. A, Donnell, R. L., & Kania, S. A. (2006). Oestrogen receptor evaluation in Pomeranian dogs with hair cycle arrest (alopecia X) on melatonin supplementation. Veterinary Dermatology, 17(4), 252–258.

Frank, L. A, Hnilica, K. A., Rohrbach, B. W., & Oliver, J. W. (2003). Retrospective evaluation of sex hormones and steroid hormone intermediates in dogs with alopecia. Veterinary Dermatology, 14(2), 91–97.

Friend, E. (2009). Complications of wound healing. In J. Williams & A. Moores (Eds.), BSAVA Manual of canine and feline wound management and reconstruction. British Small Animal Veterinary Association.

Gonçalves, B. A. L., Vianna, L. R., & Andrade, C. C. (2019). Alopecia psicogênica em gato tratada através da Terapia Neural: relato de caso. PUBVET, 13(12), 1–6. https://doi.org/10.31533/pubvet.v13n12a463.1-6.

Gondim, A. L. C. L., & Araújo, A. K. L. (2020). Alopecia X em cães: revisão. Pubvet, 14(5), 1–8. https://doi.org/10.31533/pubvet.v14n5a573.1-8.

Gross, T. L., Ihrke, P. J., Walder, E. J., & Affolter, V. K. (2008). Skin diseases of the dog and cat: clinical and histopathologic diagnosis. John Wiley & Sons.

Hill, P. (2005). Clinical Approach to Alopecia in Dogs–Will the Hair Grow Back. The Royal School Of Veterinary Studies, 263–268.

Kim, B. J., Lim, Y. Y., Kim, H. M., Lee, Y. W., Won, C. H., Huh, C. H., & Kang, H. (2012). Hair follicle regeneration in mice after wounding by microneedle roller. International Journal of Trichology, 4(2), 117–130.

Kim, Y. S., Jeong, K. H., Kim, J. E., Woo, Y. J., Kim, B. J., & Kang, H. (2016). Repeated microneedle stimulation induces enhanced hair growth in a murine model. Annals of Dermatology, 28(5), 586–592. https://doi.org/10.5021/ad.2016.28.5.586.

Melián, C. (2004). Alopecia X in dogs. Proceedings of North American Veterinary Conference, 18, 371.

Miller, W. H., Griffin, C. E., Campbell, K. L., & Muller, G. H. (2013). Muller and Kirk’s Small Animal Dermatology. Elsevier Health Sciences.

Müntener, T., Schuepbach‐Regula, G., Frank, L., Rüfenacht, S., & Welle, M. M. (2012). Canine noninflammatory alopecia: a comprehensive evaluation of common and distinguishing histological characteristics. Veterinary Dermatology, 23(3), 206-e44.

Nuttal, T. (2010). Enfermedades cutaneas del perro y el gato. Grupoasis, Zaragoza, Espanha.

Paradis, M. (2012). An approach to symmetrical alopecia in the dog. In BSAVA Manual of Canine and Feline Dermatology (pp. 91–102). BSAVA Library.

Patel, A., & Forsythe, P. J. (2011). Dermatologia em pequenos animais. Elsevier Brasil.

Paterson, S. (2009). Manual of skin diseases of the dog and cat. John Wiley & Sons.

Stoll, S., Dietlin, C., & Nett‐Mettler, C. S. (2015). Microneedling as a successful treatment for alopecia X in two P omeranian siblings. Veterinary Dermatology, 26(5), 387-e88. https://doi.org/https://doi.org/10.1111/vde.12236.

Published

2022-11-30

Issue

Section

Medicina veterinária

How to Cite

Microneedling associated with orchiectomy as a treatment for alopecia x in a German Spitz dog. (2022). Pubvet, 16(11). https://doi.org/10.31533/pubvet.v16n11a1264.1-9