Inflammatory lesion at the injection site following rabies vaccination in a cat

Case report

Authors

  • Camili da Silva Sousa Xavier Faculdade Rebouças

DOI:

https://doi.org/10.31533/pubvet.v19n11e1866

Keywords:

Adverse reactions, cats, pyogranuloma

Abstract

Rabies vaccination in cats is essential for the prevention of rabies but may rarely cause inflammatory adverse reactions. This paper reports the case of a 3-year-old mixed-breed female cat that developed an inflammatory lesion at the injection site of her rabies vaccine. Clinical management resulted in a favorable outcome, highlighting the importance of early diagnosis and timely intervention to avoid complications.

References

Asín, J. (2019). Aluminium vaccine adjuvants in veterinary medicine: A review of efficacy and safety. Veterinary Pathology, 56(2), 282–291. https://doi.org/10.1177/0300985818809142.

Day, M. J., Horzinek, M. C., Schultz, R. D., & Squires, R. A. (2016). Diretrizes para a vacinação de cães e gatos. Journal of Small Animal Practice, 57, 699–706.

Hartmann, K., Egberink, H., Möstl, K., Addie, D. D., Belák, S., Boucraut-Baralon, C., Frymus, T., Lloret, A., Hofmann-Lehmann, R., Marsilio, F., Pennisi, M. G., Tasker, S., Thiry, E., Truyen, U., & Hosie, M. J. (2023). Feline Injection-Site Sarcoma and Other Adverse Reactions to Vaccination in Cats. In Viruses (Vol. 15, Issue 8, p. 1708). https://doi.org/10.3390/v15081708.

Leal, P. D. S., Almeida, E. C. P. A., & Lopes, C. W. G. (2016). Diagnóstico de dermatopatia piogranulomatosa por Nocardia spp. numa cadela Labrador Retriever com hipotireoidismo, Rio de Janeiro, Brasil-Relato de caso. Brazilian Journal of Veterinary Medicine, 38(2), 203–209.

Lucroy, M. D., Kugler, A. M., El-Tayyeb, F., Clauson, R. M., Kalinauskas, A. E., & Suckow, M. A. (2022). Field safety experience with an autologous cancer vaccine in tumor-bearing cats: A retrospective study of 117 cases (2015–2020). Journal of Feline Medicine and Surgery, 24(6). https://doi.org/10.1177/1098612X211031504.

Marks, S. L., Kook, P. H., Papich, M. G., Tolbert, M. K., & Willard, M. D. (2018). ACVIM consensus statement: Support for rational administration of gastrointestinal protectants to dogs and cats. Journal of Veterinary Internal Medicine, 32(6). https://doi.org/10.1111/jvim.15337.

Moore, G. E., DeSantis-Kerr, A. C., Guptill, L. F., Glickman, N. W., Lewis, H. B., & Glickman, L. T. (2007). Adverse events after vaccine administration in cats: 2,560 Cases (2002-2005). Journal of the American Veterinary Medical Association, 231(1). https://doi.org/10.2460/javma.231.1.94.

Petrovsky, N. (2015). Comparative Safety of Vaccine Adjuvants: A Summary of Current Evidence and Future Needs. Drug Safety, 38(11), 1059–1074. https://doi.org/10.1007/s40264-015-0350-4.

Reichmann, M. L. A. B., Pinto, H. B. F., & Nunes, V. F. P. (1999). Vacinação contra a raiva de cães e gatos. In I. Pasteur (Ed.), Manual Técnico do Instituto Pasteur (p. 32). https://doi.org/10.15361/2175-0106.2015v31n2p01.

Rupprecht, E. C., Hanlon, C., & Ardósia, D. (2004). Vacinação oral da vida selvagem contra a raiva: oportunidades e desafios na prevenção e controle. Developmet of Biologia, 119, 173–184.

Ryan, S., Bacon, H., Endenburg, N., Hazel, S., Jouppi, R., Lee, N., Sekel, K., & Takashima, G. (2018). Diretrizes para o bem-estar animal da WSAVA. WSAVA Global Veterinary Community, 20–23.

Ryan, S., Bacon, H., Endenburg, N., Hazel, S., Jouppi, R., Lee, N., Seksel, K., & Takashima, G. (2019). WSAVA animal welfare guidelines. The Journal of Small Animal Practice, 60(5), E1–E46. https://doi.org/10.1111/jsap.12998.

Silva, B. C., Santos, C. S., Divino, D. S. A., Donon, J. B., Ferreira, M. E. A., Gonçalves, N. B., Cobo, P. R., Oliveira, T. A. S., Reis, T. M., Sousa, V. P. S., & Mendes, W. A. (2021). Raiva em cães e gatos no Brasil: Análise descritiva. PUBVET, 15(10), 1–5. https://doi.org/10.31533/pubvet.v15n10a945.1-5.

Tolbert, K., & Stubbs, E. (2024). Rational use of gastroprotectants in cats: An evidence-based approach. Journal of Feline Medicine and Surgery, 26(8), 759–770. https://doi.org/10.1177/1098612X241274235.

Weidinger, A. K., Hartmann, K., & Bergmann, M. (2025). Vaccine-associated adverse events in cats. Tierärztliche Praxis Ausgabe K: Kleintire/Heimtiere, 53(1), 23–33. https://doi.org/10.1055/a-2514-1323.

Published

2025-11-30

Issue

Section

Medicina veterinária

How to Cite

1.
Xavier C da SS. Inflammatory lesion at the injection site following rabies vaccination in a cat: Case report. Pubvet [Internet]. 2025 Nov. 30 [cited 2026 Oct. 20];19(11):e1866. Available from: https://ojs.pubvet.com.br/index.php/revista/article/view/4311